Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HPD | P32754 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953564 | 0.88 | TDO2 (0.48) | ALDH1A1HPDPOLBPDE4DTDO2 | |
| SCHEMBL9953739 | 0.88 | HPD (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2HPD | |
| SCHEMBL9954001 | 0.86 | PDE4D (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2HPD | |
| SCHEMBL9954234 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTSMN1; SMN2HPD | |
| SCHEMBL9953800 | 0.81 | POLB (0.41) | POLBPDE4DCA12CA1CA2 | |
| SCHEMBL9953497 | 0.80 | PDE4D (0.43) | ALDH1A1KDM4EPDE4DCA12CA1 | |
| SCHEMBL9952904 | 0.78 | GLA (0.51) | MAPTPOLBTDO2IDO2HCAR1 | |
| SCHEMBL9954671 | 0.77 | HCAR1 (0.52) | HPDPDE4DTDO2IDO2HCAR1 | |
| SCHEMBL9954747 | 0.76 | HCAR1 (0.53) | ALDH1A1KDM4ESMN1; SMN2HPDPOLB | |
| SCHEMBL9953432 | 0.76 | HCAR1 (0.55) | ALDH1A1KDM4EMAPTPOLBPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |