Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 4/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953980 | 0.87 | ATM (0.51) | PI4KAPIK3CGKMT2ARXFP1MAPT | |
| SCHEMBL9954470 | 0.84 | HCAR1 (0.46) | PI4KAPIK3CGKMT2ARXFP1MAPT | |
| SCHEMBL9954543 | 0.82 | ALDH1A1 (0.58) | ALOX12KMT2ARXFP1MDM2MAPT | |
| SCHEMBL10289024 | 0.78 | SMN1; SMN2 (0.55) | PI4KAPIK3CGKMT2AMAPTMEN1 | |
| SCHEMBL10288659 | 0.78 | POLB (0.53) | PI4KAPIK3CGKMT2AMAPTMEN1 | |
| SCHEMBL9953607 | 0.77 | KMT2A (0.58) | KMT2ARXFP1MAPTGABRA1GABRA5 | |
| SCHEMBL9954958 | 0.76 | ALDH1A1 (0.47) | KMT2AMAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL16204870 | 0.75 | KMT2A (0.58) | KMT2ARXFP1RAB9AGABRA1GABRG2 | |
| SCHEMBL9955586 | 0.75 | HPD (0.44) | PI4KAPIK3CGKMT2AMEN1 | |
| SCHEMBL9954343 | 0.75 | MAPT (0.49) | KMT2AMAPTRAB9AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |