Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.44 |
| ▸ | PI4KA | P42356 | 4/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953324 | 0.87 | HCAR1 (0.50) | PI4KAPIK3CGHCAR1CA12CA1 | |
| SCHEMBL9954094 | 0.86 | HCAR1 (0.51) | HPDPI4KAPIK3CGHCAR1CA12 | |
| SCHEMBL9954374 | 0.85 | HPD (0.44) | HPDMEN1KMT2ADCTPP1HSD17B10 | |
| SCHEMBL9953665 | 0.85 | TGM2 (0.45) | HPDPI4KAPIK3CG | |
| SCHEMBL9953795 | 0.83 | SMN1; SMN2 (0.55) | HPDPI4KAPIK3CGMEN1KMT2A | |
| SCHEMBL9954546 | 0.82 | PI4KA (0.44) | PI4KAPIK3CG | |
| SCHEMBL9955061 | 0.82 | PIK3CG (0.48) | PI4KAPIK3CGMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9953980 | 0.81 | ATM (0.51) | PI4KAPIK3CGMEN1KMT2AHCAR1 | |
| SCHEMBL10289024 | 0.78 | SMN1; SMN2 (0.55) | HPDPI4KAPIK3CGMEN1KMT2A | |
| SCHEMBL9954423 | 0.78 | POLB (0.41) | PI4KAPIK3CGCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |