Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACR | P10323 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421363 | 0.94 | ALDH1A1 (0.48) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL29754225 | 0.94 | ALDH1A1 (0.48) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL1421354 | 0.88 | RAB9A (0.56) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL6070567 | 0.82 | MAPT (0.58) | RAB9AMAPTTSHRALDH1A1LOXL2 | |
| SCHEMBL40349 | 0.80 | CYP4F2 (0.51) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL69664 | 0.80 | RAB9A (0.62) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL69663 | 0.80 | RAB9A (0.62) | RAB9AMAPTCASP3SENP8SENP7 | |
| SCHEMBL5558418 | 0.78 | CYP4F2 (0.49) | RAB9AMAPTTSHRCA1CA2 | |
| SCHEMBL3539591 | 0.78 | SLC7A5 (0.45) | MAPTTSHRCA1CA2ALDH1A1 | |
| SCHEMBL5556877 | 0.77 | TP53 (0.49) | RAB9AMAPTCASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |