Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958946 | 0.82 | KMT2A (0.47) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL9955416 | 0.80 | TSHR (0.40) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL9955039 | 0.78 | ALPL (0.54) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9953570 | 0.78 | LMNA (0.55) | ALDH1A1KMT2AMAPTPOLBLMNA | |
| SCHEMBL30866828 | 0.76 | KDM4E (0.53) | ALDH1A1HPGDMAPTL3MBTL1LMNA | |
| SCHEMBL21512607 | 0.76 | KDM4E (0.53) | ALDH1A1HPGDMAPTL3MBTL1LMNA | |
| SCHEMBL9955433 | 0.76 | TSHR (0.38) | MEN1KMT2AMAPTPOLBEDNRA | |
| Formic Acid SCHEMBL14247468 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9954777 | 0.73 | PIK3CD (0.56) | MEN1KMT2AMAPTEDNRA | |
| SCHEMBL9954790 | 0.72 | SHMT2 (0.41) | ALDH1A1MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |