Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091395 | 0.78 | ALDH1A1 (0.45) | ALDH1A1POLBMAPK1MEN1MAPT | |
| SCHEMBL19657347 | 0.77 | NMT1 (0.32) | NMT1 | |
| SCHEMBL8577057 | 0.74 | ALDH1A1 (0.50) | ALDH1A1POLBMAPK1MAPTKMT2A | |
| SCHEMBL8577054 | 0.74 | — | — | |
| SCHEMBL22004780 | 0.73 | PYCR1 (0.31) | CRHR1PYCR1 | |
| SCHEMBL635998 | 0.72 | MEN1 (0.35) | ALDH1A1PYCR1POLBMAPK1MEN1 | |
| SCHEMBL1751110 | 0.71 | NMT1 (0.50) | NMT1CRHR1ALDH1A1POLBMAPK1 | |
| SCHEMBL5354779 | 0.71 | NMT1 (0.44) | NMT1CRHR1 | |
| SCHEMBL23381622 | 0.69 | GABRA1 (0.32) | NMT1CRHR1ALDH1A1POLB | |
| SCHEMBL6726449 | 0.69 | ALDH1A1 (0.44) | ALDH1A1PYCR1POLBMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| EP-2654425-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | Bayer Intellectual Property GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084852-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084852-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | EPX, CAT, PIGO | NMT1 3272/4885CRHR1 2829/4885ALDH1A1 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.