Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955356 | 0.77 | NMT1 (0.38) | NMT1 | |
| SCHEMBL19657376 | 0.69 | CCR5 (0.36) | — | |
| SCHEMBL22004780 | 0.62 | PYCR1 (0.31) | — | |
| SCHEMBL20042106 | 0.62 | CRHR1 (0.38) | — | |
| SCHEMBL10187266 | 0.62 | HRH4 (0.36) | — | |
| SCHEMBL17884680 | 0.59 | ALDH1A1 (0.48) | — | |
| SCHEMBL6726449 | 0.59 | ALDH1A1 (0.44) | — | |
| SCHEMBL2091395 | 0.58 | ALDH1A1 (0.45) | — | |
| SCHEMBL635998 | 0.58 | MEN1 (0.35) | — | |
| SCHEMBL5354779 | 0.57 | NMT1 (0.44) | NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |