Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360628 | 0.95 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10L3MBTL1L3MBTL3 | |
| SCHEMBL28206991 | 0.80 | GAA (0.35) | L3MBTL1L3MBTL3MEN1KMT2AHPGD | |
| SCHEMBL30425541 | 0.79 | GAA (0.34) | L3MBTL1L3MBTL3MEN1KMT2AHPGD | |
| SCHEMBL15941744 | 0.79 | MEN1 (0.35) | KDM4EALDH1A1L3MBTL1L3MBTL3TSHR | |
| SCHEMBL30938358 | 0.78 | CHRNB2 (0.37) | KDM4EALDH1A1HSD17B10L3MBTL1TSHR | |
| SCHEMBL30425911 | 0.74 | L3MBTL3 (0.35) | KDM4EALDH1A1L3MBTL1L3MBTL3MEN1 | |
| SCHEMBL28287138 | 0.73 | ALDH1A1 (0.38) | KDM4EALDH1A1L3MBTL1L3MBTL3TP53 | |
| SCHEMBL2552216 | 0.73 | HTR6 (0.39) | L3MBTL1L3MBTL3TSHRHPGDPOLB | |
| SCHEMBL28206590 | 0.73 | TSHR (0.49) | ALDH1A1L3MBTL1TSHRKMT2AHPGD | |
| SCHEMBL31411007 | 0.72 | USP2 (0.50) | ALDH1A1HSD17B10L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088156-A1 | INHIBITORS OF CYTOCHROME P450 | GILEAD SCIENCES, INC. (US) | 2012-06-28 | — | — | WO | disclosed |