SCHEMBL9964547

SCHEMBL9964547

Cc1cc(=O)n(-c2cc(C(=O)NS(=O)(=O)N(C)C(C)C)c(Cl)cc2F)c(=O)n1C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 18/20 0.39
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9917263 0.91 SCN9A (0.40) SCN9ACYP2C19
Saflufenacil SCHEMBL29349941 0.88 SCN9A (0.39) SCN9APOLBAPEX1
Saflufenacil SCHEMBL712168 0.88 SCN9A (0.39) SCN9APOLBAPEX1
SCHEMBL4062938 0.86 SCN9A (0.40) SCN9ACYP2C19POLBAPEX1
SCHEMBL19827391 0.84 SCN9A (0.39) SCN9ACYP2C19POLBAPEX1
SCHEMBL6049375 0.81 SCN9A (0.38) SCN9APOLBAPEX1
SCHEMBL7226426 0.81 SCN9A (0.35) SCN9APOLBAPEX1
SCHEMBL3945402 0.80 SCN9A (0.42) SCN9A
SCHEMBL6049432 0.79 SCN9A (0.36) SCN9APOLBAPEX1
SCHEMBL4065246 0.79 SCN9A (0.42) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309560-A1 SOLUBLE LIQUID COMPOSITIONS OF SAFLUFENACIL, METHOD OF PREPARATION AND USE THEREOF ADAMA AGAN LTD. (IL) 2023-10-05 US disclosed
US-20170181431-A1 HERBICIDAL COMPOSITIONS CONTAINING 4-AMINO-3-CHLORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND A CELL MEMBRANE DISRUPTOR HERBICIDE OR A DERIVATIVE THEREOF DOW AGROSCIENCES LLC (US) 2017-06-29 US disclosed
US-20170064954-A1 HERBICIDAL COMPOSITIONS CONTAINING 4-AMINO-3-CHLORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF, A TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE OR A DERIVATIVE THEREOF, AND A CELL MEMBRANE DISRUPTOR HERBICIDE OR A DERIVATIVE THEREOF DOW AGROSCIENCES LLC (US) 2017-03-09 US disclosed
US-9545104-B2 Liquid suspension concentrate formulations containing saflufenacil and glyphosate BASF SE (DE) 2017-01-17 US disclosed
US-8778838-B2 Aqueous concentrate formulations containing saflufenacil and glyphosate BASF SE (DE) 2014-07-15 US disclosed
US-8716184-B2 Herbicidal composition comprising the hydrates of saflufenacil and glyphosate or glufosinate BAYER CROPSCIENCE AG (DE) 2014-05-06 US disclosed
US-8703650-B2 Liquid suspension concentrate formulations containing saflufenacil BASF SE (DE) 2014-04-22 US disclosed
US-20120302444-A1 LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL BASF SE (DE) 2012-11-29 US disclosed
US-20120231954-A1 LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL AND GLYPHOSATE BASF SE (DE) 2012-09-13 US disclosed
US-20120157312-A1 Aqueous Concentrate Formulations Containing Saflufenacil and Glyphosate BASF SE (DE) 2012-06-21 US disclosed
US-20110212837-A1 Herbicidal Composition Comprising The Hydrates Of Saflufenacil And Glyphosate Or Glufosinate BAYER CROPSCIENCE AG (DE) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212837-A1 Herbicidal Composition Comprising The Hydrates Of Saflufenacil And Glyphosate Or Glufosinate GLUL, PFAS, GLI2 SCN9A 1151/4885CYP2C19 2070/4885POLB 912/4885
US-20230309560-A1 SOLUBLE LIQUID COMPOSITIONS OF SAFLUFENACIL, METHOD OF PREPARATION AND USE THEREOF SLCO4C1, OTC, SORD SCN9A 1507/4885CYP2C19 1045/4885POLB 1071/4885
US-20120302444-A1 LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL SCD5, FFAR3, FFAR2 SCN9A 3013/4885CYP2C19 2839/4885POLB 3348/4885
US-20120231954-A1 LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL AND GLYPHOSATE PFAS, SLC6A5, AGXT SCN9A 2385/4885CYP2C19 2458/4885POLB 3164/4885
US-20120157312-A1 Aqueous Concentrate Formulations Containing Saflufenacil and Glyphosate GLRA3, GNMT, PFAS SCN9A 2865/4885CYP2C19 3033/4885POLB 1977/4885
US-20170064954-A1 HERBICIDAL COMPOSITIONS CONTAINING 4-AMINO-3-CHLORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF, A TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE OR A DERIVATIVE THEREOF, AND A CELL MEMBRANE DISRUPTOR HERBICIDE OR A DERIVATIVE THEREOF CYP4F2, CYP4F8, CYP4F12 SCN9A 3060/4885CYP2C19 176/4885POLB 4262/4885
US-20170181431-A1 HERBICIDAL COMPOSITIONS CONTAINING 4-AMINO-3-CHLORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND A CELL MEMBRANE DISRUPTOR HERBICIDE OR A DERIVATIVE THEREOF CYP4F2, CYP4F3, CYP4F12 SCN9A 3436/4885CYP2C19 297/4885POLB 4347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.