Sugi Predict

Sugi Predict / Compounds / SCHEMBL996704

SCHEMBL996704

SCHEMBL996704

Cc1cc(C(=O)O)ccc1C#N

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MRGPRX4 Q96LA9 1/20 0.56
▸ S1PR3 Q99500 3/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ HPGD P15428 1/20 0.51
▸ TSHR P16473 2/20 0.47
▸ MYC P01106 1/20 0.47
▸ ESR1 P03372 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ PTPN7 P35236 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ GRM1 Q13255 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ NR3C2 P08235 2/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ CES2 O00748 1/20 0.43
▸ CES1 P23141 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807171 0.86 RXRA (0.51) MRGPRX4NR3C2
SCHEMBL30737737 0.85 S1PR3 (0.51) MRGPRX4S1PR3ALDH1A1TSHRMEN1
SCHEMBL3959215 0.85 ALDH1A1 (0.51) MRGPRX4ALDH1A1HPGDTSHRMYC
SCHEMBL31186416 0.85 ALDH1A1 (0.51) MRGPRX4ALDH1A1HPGDTSHRMYC
SCHEMBL2369495 0.85 S1PR3 (0.51) MRGPRX4S1PR3ALDH1A1TSHRMEN1
SCHEMBL1275282 0.83 S1PR3 (0.54) S1PR3
SCHEMBL2767509 0.83 S1PR3 (0.50) MRGPRX4S1PR3
SCHEMBL4844022 0.82 ALDH1A1 (0.59) MRGPRX4ALDH1A1HPGDTSHR
SCHEMBL29472005 0.82 ALDH1A1 (0.59) MRGPRX4ALDH1A1HPGDTSHR
SCHEMBL27141720 0.81 TSHR (0.47) MRGPRX4ALDH1A1TSHRMYCESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110144050-B With MnO4-Rare earth europium coordination polymer with detection function and preparation method thereof 西北大学 2021-06-29 — — CN claimed
CN-110144050-A One kind having MnO4-Rare-earth europium coordination polymer of detection function and preparation method thereof 西北大学 2019-08-20 — — CN claimed
EP-4695246-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 — — EP disclosed
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 — — US disclosed
CN-114656373-B Cyano-substituted benzamide compound and application thereof 南通泰禾化工股份有限公司 2025-04-15 — — CN disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 — — US disclosed
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors ENANTA PHARM INC (US) 2024-10-31 — — US disclosed
WO-2024213653-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 — — WO disclosed
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2024-04-09 — — US disclosed
EP-3687543-B1 COMBINATIONS OF PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-03-20 — — EP disclosed
CN-110997627-B Cyst amide derivatives 亥姆霍兹感染研究中心有限公司 2023-10-10 — — CN disclosed
EP-0858451-A1 PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS Astra Pharmaceuticals Limited (GB) 1998-08-19 — — EP disclosed
US-5652363-A TREATING PLATELET ACTIVATING FACTOR MEDIATED DISEASES C.D. SEARLE & CO. (US) 1997-07-29 — — US disclosed
WO-1997014686-A1 PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS ASTRA PHARMACEUTICALS LIMITED (GB) 1997-04-24 — — WO disclosed
WO-1994029307-A1 PYRROLO[3,2-B]PYRIDINYLALKYL BENZAMIDE DERIVATIVES G.D. SEARLE & CO. (US) 1994-12-22 — — WO disclosed
US-5360907-A Platelet activating factor G.D. SEARLE & CO. (US) 1994-11-01 — — US disclosed
US-5300639-A 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-05 — — US disclosed
US-5118806-A Enzyme inhibitor for lipoxygenase; useful for treating cancer, hepatic diseases, inflammation, cerebrovascular diseases TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-06-02 — — US disclosed
US-4956360-A LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-11 — — US disclosed
EP-0351856-A2 Thiazolo[5,4-b]azepine compounds Takeda Chemical Industries, Ltd. (JP) 1990-01-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors GABRA5, GABRA1, GABBR2 MRGPRX4 464/4885S1PR3 194/4885ALDH1A1 621/4885
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 MRGPRX4 464/4885S1PR3 194/4885ALDH1A1 621/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 MRGPRX4 464/4885S1PR3 194/4885ALDH1A1 621/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 MRGPRX4 488/4885S1PR3 19/4885ALDH1A1 4172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.