Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970102 | 0.73 | AOC3 (0.45) | AOC3LMNAKDM4ELOX | |
| SCHEMBL9970103 | 0.72 | AOC3 (0.44) | AOC3LMNALOX | |
| SCHEMBL9970109 | 0.67 | LMNA (0.44) | AOC3LMNAKDM4ELOX | |
| SCHEMBL9970101 | 0.64 | LMNA (0.50) | AOC3LMNAKDM4ELOX | |
| SCHEMBL9970107 | 0.63 | AOC3 (0.39) | AOC3LMNAKDM4ELOX | |
| SCHEMBL343169 | 0.62 | AOC3 (1.00) | AOC3KDM4ELOX | |
| SCHEMBL9970098 | 0.61 | LMNA (0.71) | AOC3LMNAKDM4ELOX | |
| SCHEMBL19969290 | 0.61 | LMNA (0.50) | AOC3LMNAKDM4ELOX | |
| SCHEMBL20804156 | 0.60 | LMNA (0.42) | AOC3LMNAKDM4E | |
| SCHEMBL19969259 | 0.60 | LMNA (0.49) | AOC3LMNAKDM4ELOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822542-B2 | Isoketal scavengers and mitigation of disorders involving oxidative injury | VANDERBILT UNIVERSITY (US) | 2014-09-02 | — | — | US | disclosed |
| US-20120157501-A1 | ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY | VANDERBILT UNIVERSITY | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157501-A1 | ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY | PDXK, KYNU, FN3K | AOC3 501/4885LMNA 2014/4885KDM4E 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.