Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 2/20 | 0.51 |
| ▸ | RORC | P51449 | 2/20 | 0.51 |
| ▸ | RORB | Q92753 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.48 |
| ▸ | ICMT | O60725 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | PER2 | O15055 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976718 | 0.93 | PSEN1 (0.53) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL13125230 | 0.91 | RORA (0.58) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL12593202 | 0.88 | RORA (0.61) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL13503151 | 0.88 | RORA (0.61) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL14261677 | 0.88 | RORA (0.61) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL804880 | 0.88 | RORA (0.61) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL12284774 | 0.88 | RORA (0.61) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL15396934 | 0.88 | RORA (0.61) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL12593203 | 0.87 | RORA (0.63) | RORARORCRORBPGRPSEN1 | |
| SCHEMBL8148630 | 0.83 | MAPT (0.54) | RORARORCRORBPGRPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | RORA 577/4885RORC 241/4885RORB 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.