Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | SELL | P14151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | FUT4 | P22083 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23764856 | 0.85 | ESR1 (0.45) | KDM4ELMNATDP1MAPTALDH1A1 | |
| SCHEMBL9407168 | 0.81 | KDM4E (0.67) | KDM4ELMNAMAPTCA12CA1 | |
| SCHEMBL9407166 | 0.81 | KDM4E (0.67) | KDM4ELMNAMAPTCA12CA1 | |
| SCHEMBL6357899 | 0.79 | KDM4E (0.63) | KDM4ELMNATDP1MAPTALDH1A1 | |
| SCHEMBL14595709 | 0.78 | GAA (0.49) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL18657871 | 0.78 | CA5A (0.41) | KDM4ELMNAMAPTALDH1A1TP53 | |
| SCHEMBL21584406 | 0.76 | FBP1 (0.33) | FBP1HKDC1 | |
| SCHEMBL24221611 | 0.76 | LMNA (0.48) | KDM4ELMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL24435635 | 0.76 | ESR1 (0.44) | KDM4ELMNATDP1MAPTALDH1A1 | |
| SCHEMBL22894532 | 0.75 | TTR (0.39) | LMNAMAPTALDH1A1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210251945-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-08-19 | — | — | US | disclosed |
| WO-2021155864-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-08-12 | — | — | WO | disclosed |
| US-8486898-B2 | Compounds and method for inhibiting the activity of gelatinase and collagenase | TAIPEI MEDICAL UNIVERSITY (TMU) (TW) | 2013-07-16 | — | — | US | disclosed |
| US-20120022008-A1 | Compounds and Method for Inhibiting the Activity of Gelatinase and Collagenase | CHINA MEDICAL UNIVERSITY (TW) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210251945-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | ACE, ACE2, FURIN | KDM4E 4466/4885LMNA 2707/4885TDP1 3727/4885 |
| US-20120022008-A1 | Compounds and Method for Inhibiting the Activity of Gelatinase and Collagenase | MMP2, MMP13, MMP1 | KDM4E 2767/4885LMNA 639/4885TDP1 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.