Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7764748 | 0.82 | SIGMAR1 (0.46) | CYP2A6CYP1A2SIGMAR1HTTNPSR1 | |
| SCHEMBL25971429 | 0.82 | SIGMAR1 (0.44) | CYP2A6CYP1A2SIGMAR1HTTNPSR1 | |
| SCHEMBL27248627 | 0.81 | BCHE (0.50) | CYP2A6CYP1A2SIGMAR1 | |
| SCHEMBL11438494 | 0.81 | TERT (0.59) | CYP2A6CYP1A2SIGMAR1L3MBTL1TDP1 | |
| SCHEMBL29919654 | 0.81 | TERT (0.59) | CYP2A6CYP1A2SIGMAR1L3MBTL1TDP1 | |
| SCHEMBL17268809 | 0.81 | IGLV6-57 (0.47) | L3MBTL1TDP1IGLV6-57CYP3A4ADRA2A | |
| SCHEMBL10360408 | 0.81 | CYP2A6 (0.48) | CYP2A6CYP1A2SIGMAR1HTTNPSR1 | |
| SCHEMBL21533676 | 0.81 | SIGMAR1 (0.45) | CYP2A6CYP1A2SIGMAR1HTTL3MBTL1 | |
| SCHEMBL14099744 | 0.81 | HTR1D (0.38) | CYP2A6CYP1A2SIGMAR1SLC6A4IGLV6-57 | |
| SCHEMBL10000460 | 0.80 | LMNA (0.45) | CYP2A6L3MBTL1TDP1IGLV6-57SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020218297-A1 | POLYMETHINE COMPOUND | 株式会社ADEKA | 2020-10-29 | — | — | WO | disclosed |
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER (JP) | 2017-01-19 | — | — | US | disclosed |
| US-8872422-B2 | Dinaphthyl ethylene derivativce, process for preparing it, film prepared from it, and OLED including the film | TSINGHUA UNIVERSITY (CN) | 2014-10-28 | — | — | US | disclosed |
| US-8872422-B2 | Dinaphthyl ethylene derivativce, process for preparing it, film prepared from it, and OLED including the film | TSINGHUA UNIVERSITY (CN) | 2014-10-28 | — | — | US | disclosed |
| US-8461209-B2 | Malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20080220286-A1 | Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films | TSINGHUA UNIVERSITY (CN) | 2008-09-11 | — | — | US | disclosed |
| US-20080220286-A1 | Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films | TSINGHUA UNIVERSITY (CN) | 2008-09-11 | — | — | US | disclosed |
| EP-0999220-B1 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH INC (US) | 2007-05-02 | — | — | EP | disclosed |
| US-7094869-B2 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. (US) | 2006-08-22 | — | — | US | disclosed |
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. (US) | 2006-03-23 | — | — | US | disclosed |
| US-20030139348-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. | 2003-07-24 | — | — | US | disclosed |
| US-20020111461-A1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | SOMERS TODD C (US) | 2002-08-15 | — | — | US | disclosed |
| EP-0792289-B1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GENENTECH INC (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-0999220-A2 | Low molecular weight peptidomimetic growth hormone secretagogues | Genentech, Inc. (US) | 2000-05-10 | — | — | EP | disclosed |
| US-6034216-A | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5798337-A | USED TO PROMOTE GROWTH IN MAMMALS EITHER ALONE OR IN COMBINATION WITH OTHER GROWTH PROMOTING COMPOUNDS | GENENTECH, INC. (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0792289-A1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GENENTECH, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015148-A2 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GENENTECH, INC. (US) | 1996-05-23 | — | — | WO | disclosed |
| US-4097524-A | Process for the preparation of formamides | ATLANTIC RICHFIELD COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139348-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GHSR, GHRHR, IGFBP1 | CYP2A6 4728/4885CYP1A2 4721/4885SIGMAR1 3742/4885 |
| US-20020111461-A1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GHSR, GHRHR, IGFBP1 | CYP2A6 4728/4885CYP1A2 4721/4885SIGMAR1 3742/4885 |
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GHSR, GHRHR, IGFBP1 | CYP2A6 4726/4885CYP1A2 4713/4885SIGMAR1 3884/4885 |
| US-20080220286-A1 | Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films | EED, DDT, RABL6 | CYP2A6 1744/4885CYP1A2 3092/4885SIGMAR1 3324/4885 |
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | AGTR2, MME, AGTR1 | CYP2A6 3857/4885CYP1A2 4122/4885SIGMAR1 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.