Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944744 | 0.88 | LCK (0.42) | TSHRLCKFYNALDH1A1CFD | |
| SCHEMBL10001431 | 0.84 | LCK (0.41) | TSHRLCKFYNALDH1A1CFD | |
| SCHEMBL17340080 | 0.79 | RAB9A (0.44) | ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL15158986 | 0.79 | L3MBTL1 (0.39) | TDP1PKM | |
| SCHEMBL12285464 | 0.78 | ALOX5 (0.39) | HTTLCKFYNALDH1A1KDM4E | |
| SCHEMBL14904506 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1MAPK1 | |
| SCHEMBL20348441 | 0.77 | TSHR (0.49) | TSHRHTTALDH1A1KDM4EPTGDR2 | |
| SCHEMBL20348440 | 0.77 | TSHR (0.49) | TSHRHTTALDH1A1KDM4EMYC | |
| SCHEMBL13451132 | 0.77 | LMNA (0.44) | TSHRKDM4EHSD17B10MAPK1 | |
| SCHEMBL12285929 | 0.77 | ALDH1A1 (0.41) | LCKFYNALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9995709-B2 | Substrate modification method | ARKRAY, INC. (JP) | 2018-06-12 | — | — | US | disclosed |
| US-20130105316-A1 | Substrate Modification Method | ARKRAY, INC. (JP) | 2013-05-02 | — | — | US | disclosed |