Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 6/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188805 | 1.00 | ITGB3 (0.71) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL3713178 | 1.00 | ITGB3 (0.71) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL14485445 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL14485443 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL6685168 | 0.90 | ITGB3 (0.79) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL6998950 | 0.90 | ITGB3 (0.79) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL16173575 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL15676430 | 0.89 | ITGB3 (0.71) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL8366834 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BPTPN1HDAC8BCL2 | |
| SCHEMBL22604385 | 0.89 | GAA (0.60) | ITGB3ITGA2BPTPN1HDAC8BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767158-A | FOR BLEACHING SKIN | SHISEIDO CO., LTD. (JP) | 1998-06-16 | — | — | US | claimed |
| US-20220396832-A1 | COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-12-15 | — | — | US | disclosed |
| US-11149041-B2 | Process for the preparation of gadolinium complex of (4S)-4-(4-ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9-triazaundecanedioic acid disodium (Gadoxetate disodium) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2021-10-19 | — | — | US | disclosed |
| US-20210053044-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | UNIV EMORY (US) | 2021-02-25 | — | — | US | disclosed |
| US-20200123178-A1 | Novel Process for the Preparation of Gadolinium Complex of (4S)-4-(4-Ethoxybenzyl)-3,6,9-Tris(Carboxylatomethyl)-3,6,9-Triazaundecanedioic Acid Disodium (Gadoxetate Disodium) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-04-23 | — | — | US | disclosed |
| US-20180318818-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | EMORY UNIVERSITY (US) | 2018-11-08 | — | — | US | disclosed |
| US-9700881-B2 | Heterocyclic coupling catalysts and methods related thereto | EMORY UNIVERSITY (US) | 2017-07-11 | — | — | US | disclosed |
| WO-2017070157-A1 | REDOX DEHYDRATION COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20160243534-A1 | Heterocyclic Coupling Catalysts and Methods Related Thereto | EMORY UNIVERSITY (US) | 2016-08-25 | — | — | US | disclosed |
| WO-2015054337-A1 | HETEROCYCLIC COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2005-07-14 | — | — | US | disclosed |
| WO-2005000878-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2005-01-06 | — | — | WO | disclosed |
| WO-2004048345-A2 | 2,5-DIKETOPIPERAZINES FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2004-06-10 | — | — | WO | disclosed |
| US-20020151750-A1 | Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide | CHEN JIONG JACK (US) | 2002-10-17 | — | — | US | disclosed |
| EP-1208079-A1 | ENANTIOMERICALLY-ENRICHED COMPOUNDS HAVING PHOTOCLEAVABLE BOND(S) AND METHODS RELATED THERETO | Qiagen Genomics, Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2002024631-A1 | PROCESS TO PREPARE (2S)-2-(DIPROPYLAMINO)-6-ETHOXY-2,3-DIHYDRO-1H-INDENE-5-CARBOXAMIDE | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |
| WO-2001016090-A1 | ENANTIOMERICALLY-ENRICHED COMPOUNDS HAVING PHOTOCLEAVABLE BOND(S) AND METHODS RELATED THERETO | QIAGEN GENOMICS, INC. (US) | 2001-03-08 | — | — | WO | disclosed |
| US-5767158-A | FOR BLEACHING SKIN | SHISEIDO CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |
| EP-0728469-A2 | An endermic liniment | SHISEIDO COMPANY LIMITED (JP) | 1996-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151750-A1 | Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide | QDPR, DHPS, IMPDH2 | ITGB3 4295/4885ITGA2B 3340/4885PTPN1 4671/4885 |
| US-20160243534-A1 | Heterocyclic Coupling Catalysts and Methods Related Thereto | HAT1, CBR3, CBR1 | ITGB3 4021/4885ITGA2B 4502/4885PTPN1 4227/4885 |
| US-20180318818-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | SCLY, TST, SELENOI | ITGB3 3430/4885ITGA2B 3947/4885PTPN1 4184/4885 |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | NRDC, NOD2, NGLY1 | ITGB3 4629/4885ITGA2B 4720/4885PTPN1 1046/4885 |
| US-11149041-B2 | Process for the preparation of gadolinium complex of (4S)-4-(4-ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9-triazaundecanedioic acid disodium (Gadoxetate disodium) | CA9, CA4, GLRX3 | ITGB3 839/4885ITGA2B 1133/4885PTPN1 3045/4885 |
| US-20200123178-A1 | Novel Process for the Preparation of Gadolinium Complex of (4S)-4-(4-Ethoxybenzyl)-3,6,9-Tris(Carboxylatomethyl)-3,6,9-Triazaundecanedioic Acid Disodium (Gadoxetate Disodium) | GLRX3, CA9, CA4 | ITGB3 976/4885ITGA2B 1270/4885PTPN1 3478/4885 |
| US-20210053044-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | SCLY, TST, SQOR | ITGB3 3332/4885ITGA2B 3913/4885PTPN1 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.