Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23861352 | 0.96 | ESR1 (0.52) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL21340183 | 0.80 | ESR1 (0.50) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL23861353 | 0.79 | HPGD (0.39) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL7160137 | 0.78 | CYP2D6 (0.55) | ESR1ESR2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL983097 | 0.77 | ALDH1A1 (0.60) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL9846448 | 0.76 | ESR1 (0.57) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL2788791 | 0.75 | ESR1 (0.55) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL8987443 | 0.74 | ESR1 (0.50) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL9815465 | 0.74 | ALDH1A1 (0.59) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL25710685 | 0.74 | IDO1 (0.50) | ESR1ESR2ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331959-B1 | ANIONIC CURABLE COMPOSITIONS | DESIGNER MOLECULES INC (US) | 2022-10-05 | — | — | EP | claimed |
| US-20220204696-A1 | PHENOLIC FUNCTIONALIZED POLYIMIDES AND COMPOSITIONS THEREOF | DESIGNER MOLECULES, INC | 2022-06-30 | — | — | US | claimed |
| WO-2020219852-A1 | PHENOLIC FUNCTIONALIZED POLYIMIDES AND COMPOSITIONS THEREOF | DESIGNER MOLECULES, INC. (US) | 2020-10-29 | — | — | WO | claimed |
| US-20180237668-A1 | ANIONIC CURABLE COMPOSITIONS | DESIGNER MOLECULES, INC. | 2018-08-23 | — | — | US | claimed |
| EP-3331959-A1 | ANIONIC CURABLE COMPOSITIONS | Designer Molecules, Inc. (US) | 2018-06-13 | — | — | EP | claimed |
| WO-2017027482-A1 | ANIONIC CURABLE COMPOSITIONS | DESIGNER MOLECULES, INC. (US) | 2017-02-16 | — | — | WO | claimed |
| US-20130299747-A1 | CURATIVES FOR EPOXY COMPOSITIONSERS | DESIGNER MOLECULES, INC. | 2013-11-14 | — | — | US | claimed |
| US-20130199724-A1 | CURATIVES FOR EPOXY COMPOSITIONS | DESIGNER MOLECULES, INC. (US) | 2013-08-08 | — | — | US | claimed |
| US-8431655-B2 | Curatives for epoxy compositions | DESIGNER MOLECULES, INC. (US) | 2013-04-30 | — | — | US | claimed |
| US-8344076-B2 | Prepared by the reaction of an epoxy compound and a reactive ester; adhesive | DESIGNER MOLECULES, INC. (US) | 2013-01-01 | — | — | US | claimed |
| US-7825188-B2 | Thermoplastic elastomer with acyloxyphenyl hard block segment | DESIGNER MOLECULES, INC. (US) | 2010-11-02 | — | — | US | claimed |
| US-20100249276-A1 | CURATIVES FOR EPOXY COMPOSITIONS | DESIGNER MOLECULES, INC. (US) | 2010-09-30 | — | — | US | claimed |
| WO-2008124797-A1 | CURATIVES FOR EPOXY COMPOSITIONS | DESIGNER MOLECULES, INC. (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008077140-A2 | HYDROLYTICALLY RESISTANT THERMOSET MONOMERS | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | claimed |
| WO-2008077141-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | claimed |
| US-20080142158-A1 | HYDROLYTICALLY RESISTANT THERMOSET MONOMERS | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | claimed |
| US-20080146738-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | claimed |
| US-20080017308-A1 | Derivatives of poly(styrene-co-allyl alcohol) and methods for use thereof | DESIGNER MOLECULES, INC. | 2008-01-24 | — | — | US | claimed |
| US-20070299154-A1 | Mold compositions with high adhesion to metal substrates | DESIGNER MOLECULES, INC. | 2007-12-27 | — | — | US | claimed |
| US-6211389-B1 | TREATING SPECIFICALLY DEFINED COMBINATIONS COMPRISING AN EPOXY RESIN STARTING MATERIAL AND OTHER COMPONENTS TO ORGANIC SOLVENT, A CROWN ETHER, AND A SUITABLE BASE TO CONDITIONS SUFFICIENT TO PRODUCE A TREATED EPOXY COMPOUND | DEXTER CORPORATION | 2001-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080142158-A1 | HYDROLYTICALLY RESISTANT THERMOSET MONOMERS | ESD, JMJD7, PCNA | ESR1 138/4885ESR2 1386/4885ALDH1A1 519/4885 |
| US-20100249276-A1 | CURATIVES FOR EPOXY COMPOSITIONS | ALOX5, LTC4S, ALOX15B | ESR1 322/4885ESR2 1074/4885ALDH1A1 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.