Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CASP3 | P42574 | 2/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | HTR1A | P08908 | 6/20 | 0.54 |
| ▸ | HTR7 | P34969 | 6/20 | 0.54 |
| ▸ | HTR6 | P50406 | 6/20 | 0.54 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161251 | 0.81 | ALDH1A1 (1.00) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL29619913 | 0.81 | ALDH1A1 (1.00) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL6720393 | 0.77 | MAOB (0.54) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL6720323 | 0.77 | NQO1 (0.56) | KDM4EALDH1A1HPGDMAPTVKORC1 | |
| SCHEMBL12608743 | 0.77 | MAOA (0.64) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7331388 | 0.76 | KDM4E (0.86) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL23931463 | 0.76 | HTR1A (0.60) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL19879301 | 0.75 | NPC1 (0.68) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL394209 | 0.74 | MAOA (1.00) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL16477276 | 0.74 | MAPT (0.83) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035884-B2 | Polysiloxane-polycarbonate block cocondensates with improved rheological properties | COVESTRO DEUTSCHLAND AG (DE) | 2018-07-31 | — | — | US | disclosed |
| US-9969879-B2 | Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties | COVESTRO DEUTSCHLAND AG (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20180079862-A1 | BLOCK CO-CONDENSATES OF POLYSILOXANES AND DIHYDROXYDIPHENYLCYCLOALKANE-BASED N (CO)POLYCARBONATES | COVESTRO DEUTSCHLAND AG (DE) | 2018-03-22 | — | — | US | disclosed |
| US-20180009986-A1 | FLAME-RETARDANT MOLDING COMPOUNDS CONTAINING SILOXANE-CONTAINING POLYCARBONATE BLOCK CO-CONDENSATE | COVESTRO DEUTSCHLAND AG (DE) | 2018-01-11 | — | — | US | disclosed |
| US-20170369707-A1 | FLAME-RETARDANT, GLASS FIBER-CONTAINING MOLDING COMPOUNDS CONTAINING SILOXANE-CONTAINING POLYCARBONATE BLOCK CO-CONDENSATE | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9845379-B2 | Polysiloxane-polycarbonate block cocondensates | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-19 | — | — | US | disclosed |
| US-9845378-B2 | Process for preparing polysiloxane-polycarbonate block cocondensates | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-19 | — | — | US | disclosed |
| US-9828462-B2 | Preparation of siloxane-containing block copolycarbonates by means of reactive extrusion | COVESTRO DEUTSCHLAND AG (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20170233571-A1 | Copolycarbonate Compositions with Branch Structures and Cyclic Oligomers and Improved Rheological Properties | COVESTRO DEUTSCHLAND AG (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170226340-A1 | Copolycarbonate Compositions with Branch Structures and Linear Oligomers and Improved Rheological Properties | COVESTRO DEUTSCHLAND AG (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20160244559-A1 | PREPARATION OF SILOXANE-CONTAINING BLOCK COPOLYCARBONATES BY MEANS OF REACTIVE EXTRUSION | COVESTRO DEUTSCHLAND AG (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160244560-A1 | POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES | COVESTRO DEUTSCHLAND AG (DE) | 2016-08-25 | — | — | US | disclosed |
| US-8507732-B2 | Purification of tris-hydroxyaryl compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-13 | — | — | US | disclosed |
| US-8487025-B2 | Branched melt polycarbonate with low content of defective structures | BAYER MATERIAL SCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8158745-B2 | Polycarbonates having rearrangement structures, cyclic and linear oligomers and also flow behavior | BAYER MATERIALSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-8110649-B2 | Polycarbonates comprising cyclic oligomers and having an improved flow behavior | BAYER MATERIALSCIENCE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-20110251438-A1 | PURIFICATION OF TRIS-HYDROXYARYL COMPOUNDS | BAYER MATERIALSCIENCE AG (DE) | 2011-10-13 | — | — | US | disclosed |
| US-20110251309-A1 | BRANCHED MELT POLYCARBONATE WITH LOW CONTENT OF DEFECTIVE STRUCTURES | BAYER MATERIALSCIENCE AG (DE) | 2011-10-13 | — | — | US | disclosed |
| US-20110040066-A1 | POLYCARBONATES HAVING REARRANGEMENT STRUCTURES, CYCLIC AND LINEAR OLIGOMERS AND ALSO FLOW BEHAVIOR | BAYER MATERIALSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110003945-A1 | POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR | BAYER MATERIALSCIENCE AG | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251438-A1 | PURIFICATION OF TRIS-HYDROXYARYL COMPOUNDS | SLC10A1, SLC10A6, ABCB11 | NPC1 130/4885RAB9A 1094/4885KDM4E 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.