SCHEMBL10027963

SCHEMBL10027963

CCOC(C)Oc1ccccc1NC(=O)C(C)(C)CC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.47
▸ POLB P06746 1/20 0.47
▸ KMT2A Q03164 4/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ GAA P10253 2/20 0.42
▸ PDK1 Q15118 1/20 0.41
▸ PDK2 Q15119 1/20 0.41
▸ PDK3 Q15120 1/20 0.41
▸ PDK4 Q16654 1/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ ALOX12 P18054 2/20 0.40
▸ RIPK1 Q13546 2/20 0.40
▸ TSHR P16473 2/20 0.39
▸ ATM Q13315 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ PTK2 Q05397 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027960 0.79 KDM4E (0.71) LMNAPOLBKMT2AKDM4EL3MBTL1
SCHEMBL10027971 0.78 LMNA (0.57) LMNAPOLBKMT2AKDM4EL3MBTL1
SCHEMBL1864525 0.78 LMNA (0.46) LMNAKMT2AKDM4EL3MBTL1GAA
SCHEMBL1866451 0.78 KMT2A (0.45) POLBKMT2AKDM4EL3MBTL1GAA
SCHEMBL10027970 0.77 LMNA (0.50) LMNAPOLBKMT2AKDM4EL3MBTL1
SCHEMBL10027965 0.76 GAA (0.50) LMNAPOLBKMT2AKDM4EL3MBTL1
SCHEMBL10027967 0.74 LMNA (0.49) LMNAPOLBKMT2AKDM4EL3MBTL1
SCHEMBL825407 0.74 KMT2A (0.49) LMNAPOLBKMT2AL3MBTL1PDK1
SCHEMBL14030918 0.73 KMT2A (0.54) LMNAPOLBKMT2AKDM4EL3MBTL1
SCHEMBL5879414 0.73 LMNA (0.65) LMNAPOLBKMT2AL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120021357-A1 POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME NEC CORPORATION (JP) 2012-01-26 — — US disclosed
US-7939241-B2 (Meth)acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2011-05-10 — — US disclosed
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2009-03-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method MMAB, DNMT3A, MAT1A LMNA 4190/4885POLB 672/4885KMT2A 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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