SCHEMBL10027965

SCHEMBL10027965

CCOCOc1ccccc1NC(=O)C(C)(C)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.50
▸ LMNA P02545 3/20 0.49
▸ POLB P06746 2/20 0.49
▸ KMT2A Q03164 3/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ ALDH1A1 P00352 2/20 0.45
▸ MCL1 Q07820 1/20 0.44
▸ TSHR P16473 2/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ EGFR P00533 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ PDK1 Q15118 1/20 0.43
▸ PDK2 Q15119 1/20 0.43
▸ PDK3 Q15120 1/20 0.43
▸ PDK4 Q16654 1/20 0.43
▸ PTK2 Q05397 1/20 0.42
▸ RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027970 0.88 LMNA (0.50) GAALMNAPOLBKMT2ACYP2C19
SCHEMBL10027971 0.80 LMNA (0.57) GAALMNAPOLBKMT2AKDM4E
SCHEMBL14030980 0.79 RAB9A (0.52) GAAPOLBKMT2AALDH1A1NPC1
SCHEMBL409556 0.77 LMNA (0.54) GAALMNAPOLBKMT2ACYP2C19
SCHEMBL1858961 0.77 GAA (0.51) GAALMNAPOLBKMT2ACYP2C19
SCHEMBL10027963 0.76 LMNA (0.47) GAALMNAPOLBKMT2ACYP2C19
SCHEMBL10027980 0.76 KMT2A (0.50) GAALMNAPOLBKMT2ACYP2C19
SCHEMBL10027967 0.76 LMNA (0.49) GAALMNAPOLBKMT2AKDM4E
SCHEMBL825407 0.76 KMT2A (0.49) LMNAPOLBKMT2ACYP2C19L3MBTL1
SCHEMBL10027955 0.76 KMT2A (0.80) GAALMNAPOLBKMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120021357-A1 POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME NEC CORPORATION (JP) 2012-01-26 — — US disclosed
US-7939241-B2 (Meth)acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2011-05-10 — — US disclosed
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2009-03-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method MMAB, DNMT3A, MAT1A GAA 2810/4885LMNA 4190/4885POLB 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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