Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10027965 | 0.88 | GAA (0.50) | LMNAPOLBGAAPDK1PDK2 | |
| SCHEMBL10027971 | 0.81 | LMNA (0.57) | LMNAPOLBGAAPDK1PDK2 | |
| SCHEMBL10027963 | 0.77 | LMNA (0.47) | LMNAPOLBGAAPDK1PDK2 | |
| SCHEMBL825407 | 0.77 | KMT2A (0.49) | LMNAPOLBPDK1PDK2PDK3 | |
| SCHEMBL10027967 | 0.77 | LMNA (0.49) | LMNAPOLBGAAPDK1PDK2 | |
| SCHEMBL14026905 | 0.75 | GAA (0.55) | LMNAPOLBGAATSHRKMT2A | |
| SCHEMBL10027968 | 0.75 | KMT2A (0.77) | LMNAPOLBGAATSHRKMT2A | |
| SCHEMBL1866821 | 0.74 | LMNA (0.50) | LMNAGAATSHRKMT2ACYP2C19 | |
| SCHEMBL1871151 | 0.74 | BRD4 (0.48) | LMNAPOLBGAATSHRKMT2A | |
| SCHEMBL10684049 | 0.74 | PDK1 (0.59) | LMNAPOLBPDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021357-A1 | POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME | NEC CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |
| US-7939241-B2 | (Meth)acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method | NEC CORPORATION (JP) | 2011-05-10 | — | — | US | disclosed |
| US-20090068587-A1 | (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method | NEC CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068587-A1 | (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method | MMAB, DNMT3A, MAT1A | LMNA 4190/4885POLB 672/4885GAA 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.