SCHEMBL10030396

SCHEMBL10030396

Cc1ccc(Oc2ccc(C(C)C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.60
ALDH1A1 P00352 4/20 0.58
TDP1 Q9NUW8 2/20 0.58
POLB P06746 1/20 0.58
MAPT P10636 1/20 0.58
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
ACHE P22303 2/20 0.44
MMP13 P45452 1/20 0.42
HTT P42858 1/20 0.42
HTR2A P28223 2/20 0.42
SLC6A4 P31645 2/20 0.42
KCNH2 Q12809 1/20 0.41
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
BCHE P06276 1/20 0.40
CHRNA7 P36544 1/20 0.39
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21303292 0.94 TEAD4 (0.54) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL12642916 0.94 TEAD4 (0.54) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL4366979 0.90 ALDH1A1 (0.48) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL15849015 0.90 ALDH1A1 (0.48) TEAD4ALDH1A1TDP1POLBMAPT
Diphenylether SCHEMBL27288324 0.89 HTT (0.52) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL10030391 0.87 TEAD4 (0.47) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL14823817 0.86 TEAD4 (0.54) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL18409817 0.86 TEAD4 (0.54) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL22434556 0.86 ALDH1A1 (0.50) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL22404378 0.86 ALDH1A1 (0.50) TEAD4ALDH1A1TDP1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368595-A1 NOVEL MOLECULES Xeniopro GmbH (DE) 2025-12-04 US claimed
US-20250368595-A1 NOVEL MOLECULES Xeniopro GmbH (DE) 2025-12-04 US disclosed
US-12030855-B2 Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts CELLESTIA BIOTECH AG (CH) 2024-07-09 US disclosed
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2023-05-11 US disclosed
US-20220249500-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2022-08-11 US disclosed
US-10988596-B2 Method for stabilising a composition made from poly(arylene-ether-ketone) (PAEK) ARKEMA FRANCE (FR) 2021-04-27 US disclosed
WO-2020246566-A1 MAIN CHAIN SCISSION-TYPE RESIST MATERIAL AND COMPOSITION COMPRISING SAME 株式会社日本触媒 2020-12-10 WO disclosed
US-10815420-B2 Proppant comprising a crosslinked polymer for treatment of subterranean formations HALLIBURTON ENERGY SERVICES, INC. (US) 2020-10-27 US disclosed
EP-3086316-B1 SOUND ABSORBING AND INSULATING MATERIAL AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR CO LTD (KR) 2019-07-31 EP disclosed
US-10329270-B2 Heteroaryl compounds as BTK inhibitors and uses thereof MERCK PATENT GMBH (DE) 2019-06-25 US disclosed
US-20100252818-A1 PHOSPHAPHENANTHRENE COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME INKTEC CO., LTD. (KR) 2010-10-07 US disclosed
US-7645741-B2 Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents; bioavailability; coupling; chemical intermediates AEGERA THERAPEUTICS, INC. 2010-01-12 US disclosed
US-20090326003-A1 PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS GLAXO GROUP LIMITED (GB) 2009-12-31 US disclosed
US-7462625-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2008-12-09 US disclosed
US-20080207525-A1 Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents; bioavailability; coupling; chemical intermediates PHARMASCIENCE INC. (CA) 2008-08-28 US disclosed
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-09-06 US disclosed
US-20070042202-A1 Double-sided metallic laminate and method for manufacturing the same LG CHEM, LTD. (KR) 2007-02-22 US disclosed
US-7179815-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-02-20 US disclosed
US-7179815-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-02-20 US disclosed
US-7166603-B2 Dihydropyrimidone inhibitors of calcium channel function BRISTOL-MYERS SQUIBB CO. (US) 2007-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326003-A1 PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS PDE4A, PDE4B, PDE12 TEAD4 1079/4885ALDH1A1 692/4885TDP1 713/4885
US-20220249500-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR TEAD4 81/4885ALDH1A1 1806/4885TDP1 1357/4885
US-20100252818-A1 PHOSPHAPHENANTHRENE COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME DDT, PPOX, ODC1 TEAD4 2267/4885ALDH1A1 923/4885TDP1 2028/4885
US-20250368595-A1 NOVEL MOLECULES MUSK, IKZF3, TYR TEAD4 647/4885ALDH1A1 950/4885TDP1 1546/4885
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR TEAD4 81/4885ALDH1A1 1806/4885TDP1 1357/4885
US-20080207525-A1 Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents; bioavailability; coupling; chemical intermediates BIRC5, XIAP, BAX TEAD4 1130/4885ALDH1A1 3619/4885TDP1 676/4885
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR TEAD4 4828/4885ALDH1A1 3443/4885TDP1 2695/4885
US-12030855-B2 Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts ADH1C, ADH1A, DDC TEAD4 2691/4885ALDH1A1 42/4885TDP1 3274/4885
US-10329270-B2 Heteroaryl compounds as BTK inhibitors and uses thereof BTK, SYK, LCK TEAD4 2074/4885ALDH1A1 4570/4885TDP1 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.