Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721054 | 0.88 | MAPK1 (0.57) | ALDH1A1MAPK1HDAC8MAPTPOLB | |
| SCHEMBL130408 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPK1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7000380 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPK1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7000701 | 0.84 | SMN1; SMN2 (0.64) | ALDH1A1MAPK1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10033014 | 0.84 | RORC (0.63) | ALDH1A1MAPK1HDAC8HDAC1HDAC6 | |
| SCHEMBL10033005 | 0.84 | TDP1 (0.63) | ALDH1A1HDAC8HDAC1HDAC6MAPT | |
| SCHEMBL12505394 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPK1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL30492996 | 0.80 | SMN1; SMN2 (0.68) | ALDH1A1MAPK1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL1851780 | 0.80 | SMN1; SMN2 (0.68) | ALDH1A1MAPK1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL30355120 | 0.79 | LMNA (0.66) | ALDH1A1MAPK1MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753365-B2 | Methods of treating fibrosis | NOGRA PHARMA LIMITED (IE) | 2023-09-12 | — | — | US | disclosed |
| US-11753365-B2 | Methods of treating fibrosis | NOGRA PHARMA LIMITED (IE) | 2023-09-12 | — | — | US | disclosed |
| US-20220354809-A1 | Alkylamido Compounds and Uses Thereof | NOGRA PHARMA LIMITED (IE) | 2022-11-10 | — | — | US | disclosed |
| US-20220033346-A1 | METHODS OF TREATING FIBROSIS | NOGRA PHARMA LIMITED (IE) | 2022-02-03 | — | — | US | disclosed |
| US-20210113505-A1 | METHODS OF TREATING HAIR RELATED CONDITIONS | NOGRA PHARMA LTD (IE) | 2021-04-22 | — | — | US | disclosed |
| US-10959970-B2 | Methods of treating hair related conditions | NOGRA PHARMA LIMITED (IE) | 2021-03-30 | — | — | US | disclosed |
| US-20200383942-A1 | Alkylamido Compounds and Uses Thereof | NOGRA PHARMA LIMITED (IE) | 2020-12-10 | — | — | US | disclosed |
| US-20200188340-A1 | Methods of Treating Hair Related Conditions | GIULIANI INTERNATIONAL, LTD. (IE) | 2020-06-18 | — | — | US | disclosed |
| US-20190269637-A1 | Alkylamido Compounds and Uses Thereof | GIULIANI INTERNATIONAL, LTD. (IE) | 2019-09-05 | — | — | US | disclosed |
| US-10398667-B2 | Methods of treating hair related conditions | NOGRA PHARMA LIMITED (IE) | 2019-09-03 | — | — | US | disclosed |
| US-20150087678-A1 | METHODS OF TREATING LACTOSE INTOLERANCE | NOGRA PHARMA LIMITED (IE) | 2015-03-26 | — | — | US | disclosed |
| US-20150087678-A1 | METHODS OF TREATING LACTOSE INTOLERANCE | NOGRA PHARMA LIMITED (IE) | 2015-03-26 | — | — | US | disclosed |
| US-20150051285-A1 | Alkylamido Compounds and Uses Thereof | NOGRA PHARMA LIMITED (IE) | 2015-02-19 | — | — | US | disclosed |
| US-20150051285-A1 | Alkylamido Compounds and Uses Thereof | NOGRA PHARMA LIMITED (IE) | 2015-02-19 | — | — | US | disclosed |
| US-8796334-B2 | Methods of treating hair related conditions | NOGRA PHARMA LIMITED (IE) | 2014-08-05 | — | — | US | disclosed |
| US-8796334-B2 | Methods of treating hair related conditions | NOGRA PHARMA LIMITED (IE) | 2014-08-05 | — | — | US | disclosed |
| US-8754127-B2 | Alkylamido compounds and uses thereof | NOGRA PHARMA LIMITED (IE) | 2014-06-17 | — | — | US | disclosed |
| US-8754127-B2 | Alkylamido compounds and uses thereof | NOGRA PHARMA LIMITED (IE) | 2014-06-17 | — | — | US | disclosed |
| US-20120053245-A1 | Methods of Treating Hair Related Conditions | GIULIANI INTERNATIONAL, LTD. (IE) | 2012-03-01 | — | — | US | disclosed |
| US-20120053244-A1 | Alkylamido Compounds and Uses Thereof | NOGRA PHARMA LIMITED (IE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220354809-A1 | Alkylamido Compounds and Uses Thereof | EGFR, PPARG, ERBB3 | ALDH1A1 2715/4885MAPK1 1192/4885HDAC8 697/4885 |
| US-20190269637-A1 | Alkylamido Compounds and Uses Thereof | EGFR, PPARG, ERBB3 | ALDH1A1 2715/4885MAPK1 1192/4885HDAC8 697/4885 |
| US-20200383942-A1 | Alkylamido Compounds and Uses Thereof | EGFR, PPARG, ERBB3 | ALDH1A1 2715/4885MAPK1 1192/4885HDAC8 697/4885 |
| US-20150051285-A1 | Alkylamido Compounds and Uses Thereof | EGFR, PPARG, ERBB3 | ALDH1A1 2715/4885MAPK1 1192/4885HDAC8 697/4885 |
| US-11753365-B2 | Methods of treating fibrosis | MMP1, MMP8, FABP2 | ALDH1A1 664/4885MAPK1 4456/4885HDAC8 815/4885 |
| US-20120053245-A1 | Methods of Treating Hair Related Conditions | PPARA, PPARG, PPARD | ALDH1A1 159/4885MAPK1 3982/4885HDAC8 161/4885 |
| US-20210113505-A1 | METHODS OF TREATING HAIR RELATED CONDITIONS | EBP, AADAT, ALDH7A1 | ALDH1A1 53/4885MAPK1 2730/4885HDAC8 472/4885 |
| US-20150087678-A1 | METHODS OF TREATING LACTOSE INTOLERANCE | LCT, LPL, PPARG | ALDH1A1 530/4885MAPK1 3839/4885HDAC8 521/4885 |
| US-10398667-B2 | Methods of treating hair related conditions | PPARA, PPARG, PPARD | ALDH1A1 159/4885MAPK1 3982/4885HDAC8 161/4885 |
| US-10959970-B2 | Methods of treating hair related conditions | PPARA, PPARG, PPARD | ALDH1A1 159/4885MAPK1 3982/4885HDAC8 161/4885 |
| US-20200188340-A1 | Methods of Treating Hair Related Conditions | PPARA, PPARG, PPARD | ALDH1A1 159/4885MAPK1 3982/4885HDAC8 161/4885 |
| US-20120053244-A1 | Alkylamido Compounds and Uses Thereof | EGFR, PPARG, ERBB3 | ALDH1A1 2715/4885MAPK1 1192/4885HDAC8 697/4885 |
| US-20220033346-A1 | METHODS OF TREATING FIBROSIS | MMP1, MMP8, FABP2 | ALDH1A1 664/4885MAPK1 4456/4885HDAC8 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.