Sugi Predict

Sugi Predict / Compounds / SCHEMBL10001722

SCHEMBL10001722

SCHEMBL10001722

CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 3/20 0.70
▸ TRPM8 Q7Z2W7 5/20 0.53
▸ TRPA1 O75762 2/20 0.53
▸ SLC1A2 P43004 3/20 0.42
▸ SLC1A1 P43005 2/20 0.42
▸ KCNA5 P22460 1/20 0.41
▸ TRPV1 Q8NER1 3/20 0.41
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ GRM8 O00222 1/20 0.39
▸ GRM6 O15303 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ GRM5 P41594 1/20 0.39
▸ PMP22 Q01453 1/20 0.39
▸ GRM1 Q13255 1/20 0.39
▸ GRM2 Q14416 1/20 0.39
▸ GRM3 Q14832 1/20 0.39
▸ GRM4 Q14833 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3958539 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
SCHEMBL1150651 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
SCHEMBL3958542 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
SCHEMBL464850 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
SCHEMBL6128484 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
SCHEMBL10034575 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
SCHEMBL12381602 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
SCHEMBL2637678 1.00 EPHX1 (0.70) EPHX1TRPM8TRPA1SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL21331609 0.98 EPHX1 (0.68) EPHX1TRPM8TRPA1SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL291654 0.98 EPHX1 (0.68) EPHX1TRPM8TRPA1SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806481-B Separation and purification method of L-menthyl formic acid 安徽丰乐香料有限责任公司 2024-11-22 — — CN claimed
CN-115806481-B Separation and purification method of L-menthyl formic acid 安徽丰乐香料有限责任公司 2024-11-22 — — CN disclosed
CN-115806481-A Separation and purification method of L-menthyl formic acid 安徽丰乐香料有限责任公司 2023-03-17 — — CN disclosed
EP-2318356-B1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS PROCTER & GAMBLE (US) 2015-03-11 — — EP disclosed
US-20140186272-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2014-07-03 — — US disclosed
US-20140186272-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2014-07-03 — — US disclosed
US-8754259-B2 Synthesis of cyclohexane derivatives useful as sensates in consumer products THE PROCTER & GAMBLE COMPANY (US) 2014-06-17 — — US disclosed
US-8754259-B2 Synthesis of cyclohexane derivatives useful as sensates in consumer products THE PROCTER & GAMBLE COMPANY (US) 2014-06-17 — — US disclosed
US-20130216486-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2013-08-22 — — US disclosed
US-20130216486-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2013-08-22 — — US disclosed
US-8426643-B2 Synthesis of cyclohexane derivatives useful as sensates in consumer products THE PROCTER & GAMBLE COMPANY (US) 2013-04-23 — — US disclosed
US-8426643-B2 Synthesis of cyclohexane derivatives useful as sensates in consumer products THE PROCTER & GAMBLE COMPANY (US) 2013-04-23 — — US disclosed
US-20120283469-A1 INTERCONVERSION BETWEEN ISOMERIC P-MENTHANE-3-CARBOXYLIC ACIDS PINOVA HOLDINGS, INC 2012-11-08 — — US disclosed
US-20120116113-A1 PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS RENESSENZ LLC 2012-05-10 — — US disclosed
US-20120116113-A1 PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS RENESSENZ LLC 2012-05-10 — — US disclosed
US-20100076080-A1 Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products THE PROCTER & GAMBLE COMPANY 2010-03-25 — — US disclosed
US-20100076080-A1 Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products THE PROCTER & GAMBLE COMPANY 2010-03-25 — — US disclosed
WO-2010019730-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2010-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140186272-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS NISCH, TRPM4, TRPM8 EPHX1 528/4885TRPM8 3/4885TRPA1 10/4885
US-20100076080-A1 Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products NISCH, TRPM4, TRPM8 EPHX1 528/4885TRPM8 3/4885TRPA1 10/4885
US-20120283469-A1 INTERCONVERSION BETWEEN ISOMERIC P-MENTHANE-3-CARBOXYLIC ACIDS ME1, TASP1, MNS1 EPHX1 255/4885TRPM8 1087/4885TRPA1 781/4885
US-20120116113-A1 PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS ME3, MDH2, ME2 EPHX1 238/4885TRPM8 571/4885TRPA1 1863/4885
US-20130216486-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS NISCH, TRPM4, TRPM8 EPHX1 528/4885TRPM8 3/4885TRPA1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.