SCHEMBL1004330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL980660	0.88	NPSR1 (0.40)	NPSR1MAOAALDH1A1CYP1B1MAPT
	SCHEMBL5400415	0.82	ALDH1A1 (0.62)	CYP1A2MAOAERBB2FYNACHE
	SCHEMBL31399264	0.82	ALDH1A1 (0.62)	CYP1A2MAOAERBB2FYNACHE
	SCHEMBL27671350	0.78	CYP1A2 (0.47)	NPSR1CYP1A2MAOAERBB2FYN
	SCHEMBL730070	0.77	ALDH1A1 (0.61)	NPSR1CYP1A2MAOAERBB2FYN
	SCHEMBL2043406	0.77	ALDH1A1 (0.62)	CYP1A2MAOAERBB2FYNACHE
	SCHEMBL9193851	0.77	ERN1 (0.36)	NPSR1MAOACYP1B1MAPTKMT2A
	SCHEMBL5010127	0.76	NPSR1 (0.44)	NPSR1CYP1A2MAOAERBB2FYN
	SCHEMBL5379623	0.76	CYP1A2 (0.50)	NPSR1CYP1A2MAOAERBB2FYN
	SCHEMBL27995795	0.75	CYP1A2 (0.46)	NPSR1CYP1A2MAOAERBB2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.