Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21771177 | 0.81 | ALDH1A1 (0.33) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL10045297 | 0.74 | APP (0.49) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL29732980 | 0.74 | APP (0.63) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL845603 | 0.74 | APP (0.63) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL734280 | 0.72 | CYP2A6 (0.50) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL10045294 | 0.70 | APP (0.68) | CYP2A6ASIC3LOXL2CA2APP | |
| SCHEMBL3149296 | 0.70 | CYP2A6 (0.48) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL21177766 | 0.70 | CYP2A6 (0.48) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL6651277 | 0.70 | CYP2A6 (0.48) | CYP2A6ASIC3LOXL2MGLLBCL2L1 | |
| SCHEMBL21322484 | 0.70 | CYP2A6 (0.48) | CYP2A6ASIC3LOXL2MGLLBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145492-A1 | ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS | CANON KK (JP) | 2023-05-11 | — | — | US | disclosed |
| WO-2021132930-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE | 엘티소재주식회사 | 2021-07-01 | — | — | WO | disclosed |
| EP-3162806-A2 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | Heesung Material Ltd. (KR) | 2017-05-03 | — | — | EP | disclosed |
| EP-2906567-A1 | AROMATIC AZA-BICYCLIC COMPOUNDS COMPRISING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014067598-A1 | AROMATIC AZA-BICYCLIC COMPOUNDS COMPRISING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-05-08 | — | — | WO | disclosed |
| US-8653258-B2 | Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20120165356-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2012-06-28 | — | — | US | disclosed |
| US-8120022-B2 | Light emitting device material and light emitting device | TORAY INDUSTRIES, INC. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8120022-B2 | Light emitting device material and light emitting device | TORAY INDUSTRIES, INC. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20110218186-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2011-09-08 | — | — | US | disclosed |
| US-20100187520-A1 | LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE | TORAY INDUSTRIES, INC. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100187520-A1 | LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE | TORAY INDUSTRIES, INC. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-7638527-B2 | Spirocyclic heterocyclic derivatives and methods of their use | ADOLOR CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-7544426-B2 | Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency | CANON KABUSHIKI KAISHA (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20080102031-A1 | Spirocyclic Heterocyclic Derivatives And Methods Of Their Use | ADOLOR CORPORATION (US) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218186-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | OPRK1, OPRD1, OPRL1 | CYP2A6 137/4885ASIC3 714/4885LOXL2 1677/4885 |
| US-20080102031-A1 | Spirocyclic Heterocyclic Derivatives And Methods Of Their Use | OPRK1, OPRD1, OPRL1 | CYP2A6 137/4885ASIC3 714/4885LOXL2 1677/4885 |
| US-20120165356-A1 | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE | OPRK1, OPRD1, OPRL1 | CYP2A6 137/4885ASIC3 714/4885LOXL2 1677/4885 |
| US-20100187520-A1 | LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE | LEF1, CRY1, SOD1 | CYP2A6 1291/4885ASIC3 3586/4885LOXL2 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.