Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | BMP1 | P13497 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299209 | 1.00 | KDM4E (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12632549 | 1.00 | KDM4E (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL20328839 | 0.85 | KDM4E (0.52) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4990551 | 0.84 | BMP1 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL17623527 | 0.83 | KDM4E (0.48) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4704123 | 0.83 | BMP1 (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4988312 | 0.83 | BMP1 (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12354387 | 0.81 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL928644 | 0.81 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL27447128 | 0.81 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092256-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-02 | — | — | WO | disclosed |
| WO-2022109058-A1 | NUCLEASES COMPRISING CELL PENETRATING PEPTIDE SEQUENCES | ENTRADA THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| US-10329558-B2 | Method for producing compound containing heterocycle | THE UNIVERSITY OF TOKYO (JP) | 2019-06-25 | — | — | US | disclosed |
| US-10197567-B2 | Azoline compound and azole compound library and method for producing same | THE UNIVERSITY OF TOKYO (JP) | 2019-02-05 | — | — | US | disclosed |
| US-20170318932-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND MALIC ACID | L'OREAL (FR) | 2017-11-09 | — | — | US | disclosed |
| US-9757318-B2 | Process for relaxing keratin fibres | L'OREAL (FR) | 2017-09-12 | — | — | US | disclosed |
| EP-2029095-B1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'ORÉAL (FR) | 2017-08-30 | — | — | EP | disclosed |
| US-9743736-B2 | Method for straightening human hair fibers using heating means and malic acid | L'OREAL (FR) | 2017-08-29 | — | — | US | disclosed |
| US-9676907-B2 | Methods and systems of graft polymerization on a functionalized substrate | ASPEN RESEARCH CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170035175-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND MALIC ACID | L'OREAL (FR) | 2017-02-09 | — | — | US | disclosed |
| US-7879827-B2 | such as 5-amino-2-(2-Acetylamino-3-mercapto-propionyloxy)-benzoic acid, useful for the treatment of gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome, and for the prevention/treatment of colon cancer | ANTIBE THERAPEUTICS INC. (CA) | 2011-02-01 | — | — | US | disclosed |
| US-7879827-B2 | such as 5-amino-2-(2-Acetylamino-3-mercapto-propionyloxy)-benzoic acid, useful for the treatment of gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome, and for the prevention/treatment of colon cancer | ANTIBE THERAPEUTICS INC. (CA) | 2011-02-01 | — | — | US | disclosed |
| US-20090233886-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2009-09-17 | — | — | US | disclosed |
| US-20090233886-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2009-09-17 | — | — | US | disclosed |
| US-7498355-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2009-03-03 | — | — | US | disclosed |
| US-7498355-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2009-03-03 | — | — | US | disclosed |
| US-20080207564-A1 | Derivaitves of 4-Or 5-Aminosalicylic Acid | ANTIBE THERAPEUTICS INC. (CA) | 2008-08-28 | — | — | US | disclosed |
| US-20080207564-A1 | Derivaitves of 4-Or 5-Aminosalicylic Acid | ANTIBE THERAPEUTICS INC. (CA) | 2008-08-28 | — | — | US | disclosed |
| US-20070197479-A1 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197479-A1 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329558-B2 | Method for producing compound containing heterocycle | VIP, DNPEP, PREP | KDM4E 2288/4885MAPT 4580/4885THRB 4520/4885 |
| US-20080207564-A1 | Derivaitves of 4-Or 5-Aminosalicylic Acid | CBS, SI, TST | KDM4E 422/4885MAPT 2229/4885THRB 4276/4885 |
| US-20170035175-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND MALIC ACID | KRT18, HOGA1, CYP11A1 | KDM4E 1028/4885MAPT 482/4885THRB 2472/4885 |
| US-20090233886-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | CBS, SI, APC | KDM4E 739/4885MAPT 3407/4885THRB 4135/4885 |
| US-10197567-B2 | Azoline compound and azole compound library and method for producing same | PEPD, DAO, ANPEP | KDM4E 3568/4885MAPT 4136/4885THRB 812/4885 |
| US-20170318932-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND MALIC ACID | KRT18, HOGA1, KLK5 | KDM4E 963/4885MAPT 374/4885THRB 3291/4885 |
| US-20070197479-A1 | Derivatives of 4- or 5-aminosalicylic acid | CBS, SI, APC | KDM4E 739/4885MAPT 3407/4885THRB 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.