SCHEMBL1005535

SCHEMBL1005535

Oc1cc(-c2ccc(F)cc2)ccc1-c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 1/20 0.50
ERCC4 Q92889 1/20 0.50
APP P05067 1/20 0.46
ALOX5 P09917 4/20 0.44
CLK1 P49759 1/20 0.44
CLK2 P49760 1/20 0.44
DYRK1A Q13627 1/20 0.44
DYRK2 Q92630 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
ESR2 Q92731 1/20 0.43
EGFR P00533 1/20 0.43
PDK2 Q15119 1/20 0.43
PIK3CA P42336 1/20 0.42
BCL2L1 Q07817 1/20 0.41
BAD Q92934 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14831922 0.88 CA3 (0.54) ERCC1ERCC4ALOX5CLK1CLK2
SCHEMBL6068025 0.84 ALOX5 (0.61) APPALOX5HSD17B1HSD17B2ESR2
SCHEMBL5687977 0.80 TSHR (0.43) ERCC1ERCC4APPALOX5ESR2
SCHEMBL17625678 0.80 ALOX5 (0.68) APPALOX5HSD17B1HSD17B2ESR2
SCHEMBL17251288 0.80 PTGS2 (0.48) ERCC1ERCC4APPCLK1CLK2
Hydrochloric Acid SCHEMBL5685432 0.79 TSHR (0.42) ERCC1ERCC4APPESR2PIK3CA
SCHEMBL1005885 0.78 ALOX5 (0.70) APPALOX5ESR2EGFRBCL2L1
SCHEMBL26936632 0.77 ERCC1 (0.47) ERCC1ERCC4APPALOX5HSD17B1
SCHEMBL5843336 0.77 ALOX15 (0.74) ERCC1ERCC4APPALOX5HSD17B1
SCHEMBL1006436 0.76 MCL1 (0.52) APPALOX5EGFRPDK2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
CN-114514261-B Polyphenylene ether composition 旭化成株式会社 2024-09-10 CN disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
CN-112812291-B Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2023-07-18 CN disclosed
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
US-20220356302-A1 POLYPHENYLENE ETHER COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-11-10 US disclosed
EP-4039728-A1 POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2022-08-10 EP disclosed
CN-114514261-A Polyphenylene ether composition 旭化成株式会社 2022-05-17 CN disclosed
CN-110387037-B Polyphenylene ether and process for producing the same 旭化成株式会社 2022-05-13 CN disclosed
EP-2628759-B1 POLYPHENYLENE ETHER AS WELL AS RESIN COMPOSITION AND MOLDING THEREOF ASAHI CHEMICAL IND (JP) 2021-06-30 EP disclosed
US-8865811-B2 2014-10-21 US disclosed
US-8637631-B2 Polyphenylene ether and method for producing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-01-28 US disclosed
US-20130245182-A1 POLYPHENYLENE ETHER POWDER AND POLYPHENYLENE ETHER RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-09-19 US disclosed
US-20130231430-A1 POLYPHENYLENE ETHER, RESIN COMPOSITION, AND MOLDED BODY OF RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-09-05 US disclosed
EP-2628760-A1 POLYPHENYLENE ETHER POWDER AND POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
EP-2628759-A1 POLYPHENYLENE ETHER AS WELL AS RESIN COMPOSITION AND MOLDING THEREOF Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
US-8445573-B2 Polyphenylene ether resin composition having narrow molecular weight distribution ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-05-21 US disclosed
US-20120309925-A1 POLYPHENYLENE ETHER AND METHOD FOR PRODUCING THE SAME ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-12-06 US disclosed
US-20110166269-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-07-07 US disclosed
EP-2277951-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION Asahi Kasei Chemicals Corporation (JP) 2011-01-26 EP disclosed