Sugi Predict

Sugi Predict / Compounds / SCHEMBL1006233

SCHEMBL1006233

SCHEMBL1006233

[CH2]CCCCCCCCCCc1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CALM1 P0DP23 1/20 0.58
▸ ALOX15 P16050 2/20 0.56
▸ IGF1R P08069 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ TAAR1 Q96RJ0 1/20 0.53
▸ ALOX5 P09917 1/20 0.49
▸ MAOB P27338 2/20 0.48
▸ SIGMAR1 Q99720 1/20 0.47
▸ AOC3 Q16853 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ IDO1 P14902 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7730468 1.00 CALM1 (0.58) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL1119461 1.00 CALM1 (0.58) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL1119607 0.98 CALM1 (0.60) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL1119420 0.92 CALM1 (0.62) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL9022094 0.91 TDP1 (0.63) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL9021213 0.91 TDP1 (0.63) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL9021093 0.91 TDP1 (0.63) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL9021189 0.91 TDP1 (0.63) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL9021184 0.91 TDP1 (0.63) CALM1ALOX15IGF1RTDP1L3MBTL1
SCHEMBL9022452 0.91 TDP1 (0.63) CALM1ALOX15IGF1RTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140275463-A1 ORGANOSILICON COMPOUND AND PRODUCTION PROCESS FOR THE SAME, AND POLYSILOXANE AND PRODUCTION PROCESS FOR THE SAME CHISSO PETROCHEMICAL CORPORATION (JP) 2014-09-18 — — US disclosed
EP-1548020-B1 SILICON COMPOUND JNC CORP (JP) 2014-07-23 — — EP disclosed
US-8367792-B2 Polysiloxane compound and method of producing the same JNC CORPORATION (JP) 2013-02-05 — — US disclosed
US-20120208973-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME OOTAKE NOBUMASA (JP) 2012-08-16 — — US disclosed
EP-1550664-B1 SILICON COMPOUND JNC CORP (JP) 2012-06-27 — — EP disclosed
US-8173758-B2 Polysiloxane compound and method of producing the same JNC CORPORATION (JP) 2012-05-08 — — US disclosed
US-20110178313-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME OOTAKE NOBUMASA 2011-07-21 — — US disclosed
US-7964692-B2 Polymer obtained by addition-polymerization initiated by a silicon compound JNC CORPORATION (JP) 2011-06-21 — — US disclosed
US-7939617-B2 Silsesquioxane derivative; electronic material, optical material, optoelectronic material, paint, and primer. CHISSO CORPORATION (JP) 2011-05-10 — — US disclosed
US-7863396-B2 Silicon compounds CHISSO CORPORATION (JP) 2011-01-04 — — US disclosed
US-20050250925-A1 Silicon compound JNC CORPORATION (JP) 2005-11-10 — — US disclosed
US-20050215807-A1 Silsesquioxane derivative JNC CORPORATION (JP) 2005-09-29 — — US disclosed
EP-1550664-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-07-06 — — EP disclosed
EP-1548020-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-06-29 — — EP disclosed
US-20050033077-A1 Production process for silicon compound and the same JNC CORPORATION (JP) 2005-02-10 — — US disclosed
US-20040249103-A1 Silsesquioxane derivatives and process for production thereof JNC CORPORATION (JP) 2004-12-09 — — US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 — — US disclosed
EP-1428795-A1 SILSESQUIOXANE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF CHISSO CORPORATION (JP) 2004-06-16 — — EP disclosed
US-20040068074-A1 Production process for silsesquioxane derivative having functional group and silsesquioxane derivative JNC CORPORATION (JP) 2004-04-08 — — US disclosed
US-20040030084-A1 Production process for silsesquioxane derivative and silsesquioxane derivative JNC CORPORATION (JP) 2004-02-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178313-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME RPS4X, POLR2A, MSL1 CALM1 4579/4885ALOX15 2756/4885IGF1R 1531/4885
US-20140275463-A1 ORGANOSILICON COMPOUND AND PRODUCTION PROCESS FOR THE SAME, AND POLYSILOXANE AND PRODUCTION PROCESS FOR THE SAME PIEZO1, PFAS, MCM6 CALM1 4873/4885ALOX15 621/4885IGF1R 818/4885
US-20050215807-A1 Silsesquioxane derivative STS, SFXN1, SULT1A1 CALM1 3926/4885ALOX15 971/4885IGF1R 3663/4885
US-20120208973-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME RPS4X, POLR2A, MSL1 CALM1 4579/4885ALOX15 2756/4885IGF1R 1531/4885
US-20050033077-A1 Production process for silicon compound and the same STS, SMS, SFXN1 CALM1 4727/4885ALOX15 842/4885IGF1R 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.