Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.61 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149919 | 0.87 | ALDH1A1 (0.57) | ALDH1A1BAZ2BBAZ2ARAB9AGAA | |
| SCHEMBL1149553 | 0.86 | ALDH1A1 (1.00) | ALDH1A1BAZ2BBAZ2ARAB9AGAA | |
| SCHEMBL25815377 | 0.76 | BAZ2B (1.00) | ALDH1A1BAZ2BBAZ2ARAB9AGAA | |
| SCHEMBL1149383 | 0.76 | ALDH1A1 (0.60) | ALDH1A1BAZ2BBAZ2ARAB9AGAA | |
| SCHEMBL14150292 | 0.75 | BAZ2B (0.73) | ALDH1A1BAZ2BBAZ2ARAB9AGAA | |
| SCHEMBL10938005 | 0.75 | ALDH1A1 (0.80) | ALDH1A1BAZ2BBAZ2ARAB9AGAA | |
| SCHEMBL70354 | 0.74 | BAZ2B (0.71) | ALDH1A1BAZ2BBAZ2AGAALMNA | |
| SCHEMBL29191043 | 0.74 | BAZ2B (0.77) | ALDH1A1BAZ2BBAZ2AGAAKMT2A | |
| SCHEMBL8283442 | 0.74 | ALDH1A1 (0.57) | ALDH1A1BAZ2BBAZ2ARAB9AGAA | |
| SCHEMBL1149554 | 0.74 | RAB9A (0.66) | ALDH1A1BAZ2BBAZ2ARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902252-B2 | Inhibitors of D-amino acid oxidase | SEPRACOR, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | DDO, DAO, ACHE | ALDH1A1 465/4885BAZ2B 3409/4885BAZ2A 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.