Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633891 | 0.81 | PARP10 (0.61) | PARP10PARP3PARP4PARP15ALDH1A1 | |
| SCHEMBL12556293 | 0.79 | MAPT (0.39) | PARP10PARP4CA1CA2PARP1 | |
| SCHEMBL6454577 | 0.76 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL6054668 | 0.74 | CA1 (0.56) | SMN1; SMN2PARP10PARP15ALDH1A1KMT2A | |
| SCHEMBL2206586 | 0.74 | HTT (0.62) | HTTSMN1; SMN2PLAU | |
| SCHEMBL25512146 | 0.73 | CA1 (0.39) | SMN1; SMN2PARP10PARP3PARP4PARP15 | |
| Formic Acid Phenyl Ester SCHEMBL4873074 | 0.73 | PARP10 (0.37) | PARP10ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL11306924 | 0.72 | MAPT (0.61) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL201860 | 0.71 | CA1 (0.61) | HTTSMN1; SMN2PARP10PARP4ALDH1A1 | |
| SCHEMBL13049149 | 0.71 | HTT (0.45) | HTTSMN1; SMN2PARP10PARP4PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114857-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| US-20110144188-A1 | SALTS OF TRIMEBUTINE AND N-DESMETHYL TRIMEBUTINE | ANTIBE THERAPEUTICS INC. (CA) | 2011-06-16 | — | — | US | disclosed |
| US-20110130368-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144188-A1 | SALTS OF TRIMEBUTINE AND N-DESMETHYL TRIMEBUTINE | SI, VIP, TRIM59 | HTT 1626/4885SMN1; SMN2 1423/4885PARP10 2188/4885 |
| US-20110130368-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | CBS, SI, APC | HTT 2657/4885SMN1; SMN2 4347/4885PARP10 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.