Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784460 | 0.83 | CYP11B1 (0.30) | CYP11B1CYP11B2 | |
| SCHEMBL1106088 | 0.79 | DGAT1 (0.35) | CYP19A1CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL21828955 | 0.74 | TRPV4 (0.37) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 | |
| SCHEMBL21453401 | 0.74 | CYP3A4 (0.36) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 | |
| SCHEMBL25401613 | 0.73 | CYP17A1 (0.33) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 | |
| SCHEMBL21918095 | 0.73 | CYP1A2 (0.33) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 | |
| SCHEMBL28014496 | 0.73 | CYP19A1 (0.35) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 | |
| SCHEMBL359312 | 0.73 | CYP1A2 (0.33) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 | |
| SCHEMBL29447929 | 0.73 | CYP1A2 (0.33) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 | |
| SCHEMBL16592100 | 0.72 | VNN1 (0.38) | CYP11B1CYP11B2CYP19A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230167062-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURAL FRAGMENTS AND PREPARATION METHOD AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| EP-4052576-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURE FRAGMENT, PREPARATION METHOD THEREFOR AND USE THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2022-09-07 | — | — | EP | disclosed |
| US-10207985-B2 | Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-19 | — | — | US | disclosed |
| EP-3019476-B1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | disclosed |
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| WO-2014191737-A1 | HETEROCYCLIC COMPOUNDS AS HEDGEHOG SIGNALING PATHWAY INHIBITORS | REDX PHARMA LIMITED (GB) | 2014-12-04 | — | — | WO | disclosed |
| US-8114879-B2 | 4-piperazine-4-piperidine-1-ketone derivatives; graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis; human immunodeficiency viricides | SCHERING CORPORATION (US) | 2012-02-14 | — | — | US | disclosed |
| US-7566683-B2 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-7566683-B2 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-20080188485-A1 | PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS | SCHERING CORPORATION | 2008-08-07 | — | — | US | disclosed |
| US-7384944-B2 | Piperazine derivatives useful as CCR5 antagonists | SCHERING CORPORATION (US) | 2008-06-10 | — | — | US | disclosed |
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188485-A1 | PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS | CCR5, CXCR3, CCR2 | CYP11B1 1746/4885CYP11B2 1823/4885CYP19A1 2863/4885 |
| US-20230167062-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURAL FRAGMENTS AND PREPARATION METHOD AND APPLICATION THEREOF | AADAC, AAK1, ACLY | CYP11B1 1485/4885CYP11B2 1596/4885CYP19A1 1974/4885 |
| US-20070179295-A1 | Triazolopyrimidines | QDPR, DPYD, CYP1B1 | CYP11B1 1067/4885CYP11B2 895/4885CYP19A1 1722/4885 |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | DDT, ECE1, EBPL | CYP11B1 1333/4885CYP11B2 1413/4885CYP19A1 196/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | CYP11B1 1357/4885CYP11B2 1325/4885CYP19A1 1460/4885 |
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | OCIAD1, OCIAD2, SLCO4C1 | CYP11B1 669/4885CYP11B2 736/4885CYP19A1 922/4885 |
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | PTPN3, PHOSPHO1, SKIC3 | CYP11B1 4620/4885CYP11B2 4537/4885CYP19A1 4575/4885 |
| US-10207985-B2 | Compounds | CYP1B1, DDT, CYP1A1 | CYP11B1 40/4885CYP11B2 29/4885CYP19A1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.