Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233304 | 0.84 | MAPT (0.41) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL2231802 | 0.83 | MAPT (0.41) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL12254378 | 0.75 | MAPK1 (0.49) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL9668731 | 0.74 | MAPT (0.52) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL27777695 | 0.72 | MAPT (0.41) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL1013096 | 0.72 | CYP2C19 (0.44) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL24435144 | 0.71 | MAPT (0.40) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL4070124 | 0.71 | SLC18A3 (0.40) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL12701192 | 0.70 | MAPK1 (0.42) | MAPTTSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL28109114 | 0.70 | MAPT (0.52) | MAPTTSHRALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006336-B2 | Curable polysiloxane coating composition | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-04-14 | — | — | US | disclosed |
| EP-2838935-A1 | CURABLE POLYSILOXANE COATING COMPOSITION | 3M Innovative Properties Company (US) | 2015-02-25 | — | — | EP | disclosed |
| US-20140378608-A1 | CURABLE POLYSILOXANE COATING COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2014-12-25 | — | — | US | disclosed |
| WO-2013101477-A1 | CURABLE POLYSILOXANE COATING COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-07-04 | — | — | WO | disclosed |
| US-20130158292-A1 | METHOD FOR PRODUCING METHIONINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-20 | — | — | US | disclosed |
| US-20130150611-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-13 | — | — | US | disclosed |
| US-20130072713-A1 | METHOD FOR PRODUCING METHIONINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |
| US-8350051-B2 | Process for producing alpha-hydroxyketone compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-08 | — | — | US | disclosed |
| US-20110178309-A1 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-1372844-B1 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INST OF TECHN (US) | 2011-01-05 | — | — | EP | disclosed |
| US-6838489-B2 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | CYMETECH, LLC (US) | 2005-01-04 | — | — | US | disclosed |
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | STERLING JA, L.C. | 2003-07-31 | — | — | US | disclosed |
| US-20030083445-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | STERLING JA, L.C. | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178309-A1 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND | BCKDK, PDK4, HK1 | MAPT 3174/4885TSHR 3516/4885ALDH1A1 37/4885 |
| US-20130158292-A1 | METHOD FOR PRODUCING METHIONINE | MTR, MSMO1, MGMT | MAPT 3552/4885TSHR 2468/4885ALDH1A1 113/4885 |
| US-20130072713-A1 | METHOD FOR PRODUCING METHIONINE | MTR, MGMT, BBOX1 | MAPT 4015/4885TSHR 2048/4885ALDH1A1 182/4885 |
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | NQO1, NIT2, ALOX5 | MAPT 4167/4885TSHR 4822/4885ALDH1A1 1236/4885 |
| US-20130150611-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | ADH5, ADH1A, ADH1C | MAPT 4621/4885TSHR 975/4885ALDH1A1 33/4885 |
| US-20030083445-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | NQO1, NIT2, ALOX5 | MAPT 4167/4885TSHR 4822/4885ALDH1A1 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.