Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845433 | 0.90 | PABPC1 (0.42) | LMNAKDM4EPABPC1GAAMAPT | |
| SCHEMBL872415 | 0.84 | PABPC1 (0.38) | LMNAKDM4EPABPC1GAACYP2C9 | |
| SCHEMBL873781 | 0.82 | KDM4E (0.44) | LMNAKDM4EPABPC1GAACYP2C9 | |
| SCHEMBL845330 | 0.78 | GAA (0.47) | LMNAKDM4EPABPC1GAACYP2C9 | |
| SCHEMBL845060 | 0.76 | KDM4E (0.51) | LMNAKDM4EPABPC1GAACYP2C9 | |
| SCHEMBL845697 | 0.75 | ALDH1A1 (0.45) | PABPC1MAPTCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL845442 | 0.74 | CYP2C9 (0.43) | PABPC1MAPTCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL873858 | 0.74 | GAA (0.42) | LMNAKDM4EPABPC1GAAMAPT | |
| SCHEMBL871971 | 0.74 | PDE5A (0.42) | LMNAKDM4EPABPC1GAACYP2C9 | |
| SCHEMBL845301 | 0.73 | PABPC1 (0.51) | LMNAKDM4EPABPC1GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |