SCHEMBL1012491

SCHEMBL1012491

CC(NOCc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
MMP2 P08253 1/20 0.53
CA9 Q16790 1/20 0.53
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TSHR P16473 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LTA4H P09960 2/20 0.45
MME P08473 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SLC1A3 P43003 2/20 0.44
SLC1A2 P43004 2/20 0.44
SLC1A1 P43005 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721423 1.00 CA1 (0.53) CA1CA2MMP2CA9NPC1
SCHEMBL10659989 1.00 CA1 (0.53) CA1CA2MMP2CA9NPC1
Hydrochloric Acid SCHEMBL857895 0.98 CA1 (0.51) CA1CA2MMP2CA9NPC1
SCHEMBL4273509 0.91 CA1 (0.49) CA1CA2MMP2CA9NPC1
SCHEMBL28160114 0.86 CA1 (0.54) CA1CA2MMP2CA9NPC1
SCHEMBL724209 0.83 ALDH1A1 (0.50) CA1CA2MMP2CA9NPC1
SCHEMBL5819144 0.82 NPC1 (0.47) CA1CA2MMP2CA9NPC1
SCHEMBL28760175 0.82 CA1 (0.45) CA1CA2MMP2CA9NPC1
SCHEMBL28760174 0.82 CA1 (0.45) CA1CA2MMP2CA9NPC1
SCHEMBL28581036 0.81 MME (0.49) CA1CA2MMP2CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795198-B The method for being used to prepare gemcitabine-[phenyl (benzyloxy-l-Alanine base)] phosphate 努卡那公共有限公司 2019-09-06 CN claimed
CN-106795198-A Method for preparing gemcitabine [phenyl (benzyloxy L alaninyls)] phosphate 努卡那生物医药有限责任公司 2017-05-31 CN claimed
WO-2026100725-A1 ANTI-CCR8 ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF 住友ファーマ株式会社 2026-05-15 WO disclosed
US-12624011-B2 Oxadiazole derivative Sumitomo Pharma Co., Ltd. (JP) 2026-05-12 US disclosed
EP-3971182-B1 2-SUBSTITUTED AMINO-NAPHTH[1,2-D]IMIDAZOL-5-ONE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF PTC THERAPEUTICS INC (US) 2026-04-01 EP disclosed
US-12590063-B2 Phenol derivative Sumitomo Pharma Co., Ltd. (JP) 2026-03-31 US disclosed
US-20260042746-A1 2(1H)-PYRIDINIMINE DERATIVE Sumitomo Pharma Co., Ltd. (JP) 2026-02-12 US disclosed
US-12534442-B2 Benzisoxazole derivative Sumitomo Pharma Co., Ltd. (JP) 2026-01-27 US disclosed
US-20250382282-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2025-12-18 US disclosed
US-12427192-B2 Water soluble adjuvant and composition containing same Sumitomo Pharma Co., Ltd. (JP) 2025-09-30 US disclosed
EP-4122923-B1 OXADIAZOLE DERIVATIVE SUMITOMO PHARMA CO LTD (JP) 2025-09-10 EP disclosed
EP-1364945-A1 BENZIMIDAZOLIDINONE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2003-11-26 EP disclosed
US-20030181496-A1 Pyrrole derivatives DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2003-09-25 US disclosed
US-20030105323-A1 Pyrimidine derivative SUMITOMO PHARMACEUTICALS COMPANY LIMITED 2003-06-05 US disclosed
EP-1310485-A1 PYRROLE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2003-05-14 EP disclosed
EP-1300401-A1 FIVE-MEMBERED-RING COMPOUND SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2003-04-09 EP disclosed
US-6458798-B1 HAS AN INHIBITORY ACTIVITY OF PRODUCTION OF TH2 TYPE CYTOKINES SUCH AS IL-4, IL-5, ETC., AND IS USEFUL AS AN THERAPEUTIC AGENT FOR ALLERGIC DISEASES, AUTOIMMUNE DISEASES SUCH AS SYSTEMIC LUPUS ERYTHEMATHOSUS, ETC., AND ACQUIRED SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2002-10-01 US disclosed
EP-1110951-A1 PYRIMIDINE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-06-27 EP disclosed
US-4720484-A Peptide compounds having a nitrogenous polycyclic structure ADIR S.A.R.L. (FR) 1988-01-19 US disclosed
EP-0094815-A2 Oligopeptide prodrugs SMITHKLINE BECKMAN CORPORATION (US) 1983-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590063-B2 Phenol derivative HDAC3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HNF4A CA1 2263/4885CA2 204/4885MMP2 1645/4885
US-20260042746-A1 2(1H)-PYRIDINIMINE DERATIVE PRNP, CLN6, CDR2 CA1 1508/4885CA2 1558/4885MMP2 3104/4885
US-20250382282-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE H1-0, HTT, PRNP CA1 1172/4885CA2 904/4885MMP2 3067/4885
US-20030181496-A1 Pyrrole derivatives NCOA1, PKD1, NR3C2 CA1 4634/4885CA2 1415/4885MMP2 1364/4885
US-12427192-B2 Water soluble adjuvant and composition containing same TP53, MYD88, AQP1 CA1 2027/4885CA2 3373/4885MMP2 2146/4885
US-12624011-B2 Oxadiazole derivative HSD3B1, CBR3, CBR1 CA1 43/4885CA2 26/4885MMP2 2074/4885
US-20030105323-A1 Pyrimidine derivative IL5, IL4, IL15 CA1 4205/4885CA2 3361/4885MMP2 3133/4885
US-12534442-B2 Benzisoxazole derivative GABRA6, SLC6A1, GABRA1 CA1 818/4885CA2 601/4885MMP2 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.