Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012849 | 0.80 | IDO1 (0.41) | NPSR1TSHRHPGDHTTALDH1A1 | |
| SCHEMBL14047008 | 0.79 | HPGD (0.47) | MTNR1AMTNR1BTSHRHPGDHTT | |
| SCHEMBL749525 | 0.79 | HPGD (0.47) | MTNR1AMTNR1BTSHRHPGDHTT | |
| SCHEMBL12301716 | 0.79 | HPGD (0.47) | MTNR1AMTNR1BTSHRHPGDHTT | |
| SCHEMBL1874326 | 0.74 | ALDH1A1 (0.43) | MTNR1AMTNR1BNPSR1TSHRHPGD | |
| SCHEMBL20072234 | 0.72 | MTNR1A (0.59) | MTNR1AMTNR1BHPGD | |
| SCHEMBL1030014 | 0.72 | IDO1 (0.56) | MTNR1AMTNR1BNPSR1HPGDHTT | |
| SCHEMBL5930158 | 0.71 | ALDH1A1 (0.57) | TSHRHTTALDH1A1KMT2ALMNA | |
| SCHEMBL6695813 | 0.70 | MTNR1A (0.53) | MTNR1AMTNR1BNPSR1TSHRHPGD | |
| SCHEMBL20212336 | 0.69 | MTNR1A (0.51) | MTNR1AMTNR1BNPSR1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517880-B1 | PRODUCTION OF CIS-PELLITORIN AND USE AS A FLAVOURING | SYMRISE AG (DE) | 2011-01-05 | — | — | EP | claimed |
| EP-2496204-A2 | ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH | The Procter & Gamble Company (US) | 2012-09-12 | — | — | EP | disclosed |
| EP-2496205-A2 | ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH | The Procter & Gamble Company (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011056759-A2 | ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011056748-A2 | ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110104080-A1 | Oral Compositions for Treatment of Dry Mouth | THE PROCTER & GAMBLE COMPANY | 2011-05-05 | — | — | US | disclosed |
| US-20110104081-A1 | Oral Compositions for Treatment of Dry Mouth | THE PROCTER & GAMBLE COMPANY | 2011-05-05 | — | — | US | disclosed |
| US-7482479-B2 | Production of cis-pellitorin and use as a flavouring | SYMRISE GMBH & CO., KG (DE) | 2009-01-27 | — | — | US | disclosed |
| US-20080242740-A1 | AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS | SYMRISE GMBH & CO. KG (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080008660-A1 | Antimicrobially active compounds for treating bad breath | SYMRISE GMBH & CO. KG (DE) | 2008-01-10 | — | — | US | disclosed |
| US-20050234132-A1 | Production of cis-pellitorin and use as a flavouring | SYMRISE AG (DE) | 2005-10-20 | — | — | US | disclosed |
| US-20050208084-A1 | Use of alkylamidomandelates as flavourings | SYMRISE GMBH & CO. KG (DE) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110104081-A1 | Oral Compositions for Treatment of Dry Mouth | LPO, TAS2R40, TAS2R60 | MTNR1A 3224/4885MTNR1B 4050/4885NPSR1 2328/4885 |
| US-20110104080-A1 | Oral Compositions for Treatment of Dry Mouth | LPO, TAS2R40, TAS2R60 | MTNR1A 3224/4885MTNR1B 4050/4885NPSR1 2328/4885 |
| US-20050234132-A1 | Production of cis-pellitorin and use as a flavouring | NISCH, CYP8B1, DLAT | MTNR1A 2995/4885MTNR1B 3147/4885NPSR1 2495/4885 |
| US-20050208084-A1 | Use of alkylamidomandelates as flavourings | HNMT, TAS2R7, PNMT | MTNR1A 500/4885MTNR1B 328/4885NPSR1 2141/4885 |
| US-20080242740-A1 | AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS | TAS2R5, TAS2R20, TAS2R40 | MTNR1A 2199/4885MTNR1B 2941/4885NPSR1 489/4885 |
| US-20080008660-A1 | Antimicrobially active compounds for treating bad breath | CAT, LPO, GPX1 | MTNR1A 1225/4885MTNR1B 1136/4885NPSR1 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.