Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1017020 | 1.00 | TLR9 (0.42) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL30743067 | 0.86 | ALDH1A1 (0.40) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL29897312 | 0.85 | TLR9 (0.43) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL7694210 | 0.85 | G6PD (0.47) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL7694213 | 0.85 | G6PD (0.47) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL7697212 | 0.85 | G6PD (0.47) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL28420820 | 0.82 | G6PD (0.42) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL1211011 | 0.81 | G6PD (0.41) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL1211008 | 0.81 | G6PD (0.41) | TLR9G6PDALDH1A1STAT3CTSK | |
| SCHEMBL7693741 | 0.81 | G6PD (0.41) | TLR9G6PDALDH1A1STAT3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957226-B2 | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses | UCB PHARMA S.A. (BE) | 2015-02-17 | — | — | US | disclosed |
| US-8957226-B2 | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses | UCB PHARMA S.A. (BE) | 2015-02-17 | — | — | US | disclosed |
| US-8247595-B2 | Organic sulfur compound and its use for controlling harmful arthropod | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2152668-B1 | ORGANIC SULFUR COMPOUND AND ITS USE FOR CONTROLLING HARMFUL ARTHROPODS | SUMITOMO CHEMICAL CO (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20100160434-A1 | ORGANIC SULFUR COMPOUND AND ITS USE FOR CONTROLLING HARMFUL ARTHROPOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20090318708-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes For Preparing Them And Their Uses | UCB BIOPHARMA SPRL (BE) | 2009-12-24 | — | — | US | disclosed |
| US-20090318708-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes For Preparing Them And Their Uses | UCB BIOPHARMA SPRL (BE) | 2009-12-24 | — | — | US | disclosed |
| WO-2007031263-A1 | 4-SUBSTITUTED PYRR0LIDIN-2-0NES AND THEIR USE | UCB PHARMA, S.A. (BE) | 2007-03-22 | — | — | WO | disclosed |
| EP-1150937-A1 | LIQUID CRYSTALLINE TRIFLUORO-SUBSTITUTED COMPOUNDS | QinetiQ Limited (GB) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000039062-A1 | LIQUID CRYSTALLINE TRIFLUORO-SUBSTITUTED COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | ANPEP, DNPEP, NAAA | TLR9 1444/4885G6PD 2994/4885ALDH1A1 4716/4885 |
| US-20090318708-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes For Preparing Them And Their Uses | PPOX, PYCR1, ALDH18A1 | TLR9 4371/4885G6PD 326/4885ALDH1A1 630/4885 |
| US-20100160434-A1 | ORGANIC SULFUR COMPOUND AND ITS USE FOR CONTROLLING HARMFUL ARTHROPOD | C5, L3MBTL3, C1S | TLR9 3516/4885G6PD 1594/4885ALDH1A1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.