SCHEMBL10178735

SCHEMBL10178735

CCC(C)c1cccc(COCCOc2ccccc2C(C)=O)c1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
ALDH1A1 P00352 3/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPT P10636 4/20 0.54
L3MBTL1 Q9Y468 3/20 0.44
POLB P06746 1/20 0.43
ABCB1 P08183 1/20 0.42
KMT2A Q03164 3/20 0.42
PTK2B Q14289 1/20 0.42
HTT P42858 2/20 0.41
MEN1 O00255 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10178559 0.90 MEN1 (0.48) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL10178457 0.87 LMNA (0.60) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL10178573 0.80 KDM4E (0.48) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL10178720 0.78 ALDH1A1 (0.49) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL10178729 0.77 L3MBTL1 (0.54) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL6722042 0.76 LMNA (0.49) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL15709446 0.75 LMNA (1.00) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL30919327 0.75 LMNA (1.00) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL10178727 0.74 MAPT (0.45) LMNASMN1; SMN2ALDH1A1MAPTL3MBTL1
SCHEMBL10178744 0.74 CHRNB2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed