Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937744 | 0.80 | TRPA1 (0.41) | ALDH1A1ESR1ESR2TRPA1LMNA | |
| SCHEMBL1860042 | 0.76 | ALDH1A1 (0.44) | TYRALDH1A1ESR2TRPA1LMNA | |
| SCHEMBL27658836 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ESR1ESR2MEN1KMT2A | |
| SCHEMBL27619639 | 0.74 | ALOX5 (0.56) | ALDH1A1ESR1ESR2CNR1CNR2 | |
| SCHEMBL9468971 | 0.72 | ANPEP (0.44) | TYRESR1ESR2TRPA1LMNA | |
| SCHEMBL726663 | 0.72 | MEN1 (0.39) | ALDH1A1ESR1ESR2LMNASLC6A2 | |
| SCHEMBL726424 | 0.72 | CNR1 (0.40) | TYRALDH1A1ESR1ESR2CNR1 | |
| SCHEMBL9763719 | 0.71 | ESR2 (0.47) | TYRESR1ESR2TRPA1LMNA | |
| SCHEMBL27519877 | 0.71 | ESR1 (0.44) | ESR1ESR2TRPA1LMNACHRM1 | |
| SCHEMBL1857743 | 0.70 | ANPEP (0.41) | TYRALDH1A1ESR1ESR2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660560-B1 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-03-23 | — | — | EP | claimed |
| EP-1546249-B1 | FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-03-16 | — | — | EP | claimed |
| US-7714095-B2 | Phase transfer catalyzed method for preparation of polyetherimides | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-05-11 | — | — | US | claimed |
| JP-2009521548-A | — | — | 2009-06-04 | — | — | JP | claimed |
| EP-1660556-B1 | COPOLYETHERIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-05-13 | — | — | EP | claimed |
| EP-1966320-A2 | HIGH GLASS TRANSITION TEMPERATURE THERMOPLASTIC ARTICLES | General Electric Company (US) | 2008-09-10 | — | — | EP | claimed |
| EP-1963433-A2 | ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS | General Electric Company (US) | 2008-09-03 | — | — | EP | claimed |
| EP-1963432-A1 | EXPANDED AND EXPANDABLE HIGH GLASS TRANSITION TEMPERATURE POLYMERS | General Electric Company (US) | 2008-09-03 | — | — | EP | claimed |
| EP-1960470-A2 | FOOD SERVICE ARTICLES OF MANUFACTURE COMPRISING HIGH TEMPERATURE POLYMERS | General Electric Company (US) | 2008-08-27 | — | — | EP | claimed |
| WO-2008088336-A1 | COATED ARTICLES OF MANUFACTURE MADE OF HIGH Tg POLYMER BLENDS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-07-24 | — | — | WO | claimed |
| WO-2005021477-A2 | METHOD FOR MAKING SALTS OF HYDROXY-SUBSTITUTED HYDROCARBONS | GENERAL ELECTRIC COMPANY (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050049390-A1 | Phase transfer catalyzed method for preparation of polyetherimides | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| US-20050049439-A1 | Method for making salts hydroxy-substituted hydrocarbons | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| US-6849706-B1 | Copolyetherimides | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | claimed |
| US-6844071-B1 | Multilayer articles comprising polycarbonate and polypropylene and method for their preparation | GENERAL ELECTRIC COMPANY (US) | 2005-01-18 | — | — | US | claimed |
| US-6713598-B2 | FLAME RETARDANT WITH SPECIFIED MOLECULAR WEIGHT AND SOFTENING TEMPERATURE; REACTING PHOSPHORUS OXYHALIDE WITH HYDROXYAROMATIC COMPOUND, REACTING ARYLDIHALOPHOSPHATE WITH DIHYDROXYAROMATIC, THEN WITH HYDROXYAROMATIC | GENERAL ELECTRIC COMPANY | 2004-03-30 | — | — | US | claimed |
| US-20040044134-A1 | METHOD TO MAKE A SOLID POLYMERIC PHOSPHATE AND RESINOUS COMPOSITIONS CONTAINING IT | GENERAL ELECTRIC COMPANY | 2004-03-04 | — | — | US | claimed |
| WO-2004016685-A2 | FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2004-02-26 | — | — | WO | claimed |
| US-20040034132-A1 | Flame retardant resinous compositions and method | GENERAL ELECTRIC COMPANY | 2004-02-19 | — | — | US | claimed |
| US-20040014934-A1 | Method for the production of polyestercarbonates | GENERAL ELECTRIC COMPANY | 2004-01-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049439-A1 | Method for making salts hydroxy-substituted hydrocarbons | HDHD5, SHH, HAAO | TYR 62/4885ALDH1A1 2467/4885ESR1 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.