Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904112 | 0.90 | ADORA2A (0.43) | ADORA2ADHFRADORA1ADORA2BMEN1 | |
| SCHEMBL1033845 | 0.77 | NPC1 (0.43) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL1023476 | 0.76 | RPS6KB2 (0.37) | ADORA2ADHFRADORA1MEN1KMT2A | |
| SCHEMBL1023547 | 0.75 | MAPT (0.44) | MEN1KMT2ANPC1HSD17B10ALDH1A1 | |
| SCHEMBL1021932 | 0.74 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BHSD17B10ALDH1A1 | |
| SCHEMBL1025479 | 0.74 | TDP2 (0.41) | — | |
| SCHEMBL20392667 | 0.67 | ADORA2A (0.53) | ADORA2ADHFRADORA1ADORA2BMEN1 | |
| SCHEMBL2497304 | 0.67 | KDM4E (0.38) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27537438 | 0.67 | ADORA2A (0.53) | ADORA2ADHFRADORA1ADORA2BMEN1 | |
| SCHEMBL4011784 | 0.66 | HSD17B10 (0.52) | ADORA2ADHFRADORA1ADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315926-A1 | An Aptamer for Dengue Virus and Related Methods and Products | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-10-06 | — | — | US | claimed |
| EP-3987035-A1 | AN APTAMER FOR DENGUE VIRUS AND RELATED METHODS AND PRODUCTS | Agency for Science, Technology and Research (SG) | 2022-04-27 | — | — | EP | claimed |
| EP-3918091-A1 | METHOD OF SEQUENCING NUCLEIC ACID WITH UNNATURAL BASE PAIRS | Agency for Science, Technology and Research (SG) | 2021-12-08 | — | — | EP | claimed |
| CN-113518830-A | Method for sequencing nucleic acids with unnatural base pairing | 新加坡科技研究局 | 2021-10-19 | — | — | CN | claimed |
| WO-2020256639-A1 | AN APTAMER FOR DENGUE VIRUS AND RELATED METHODS AND PRODUCTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-12-24 | — | — | WO | claimed |
| WO-2020159435-A1 | METHOD OF SEQUENCING NUCLEIC ACID WITH UNNATURAL BASE PAIRS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-08-06 | — | — | WO | claimed |
| US-20130122506-A1 | NUCLEIC ACID BASE ANALOGS WITH QUENCHING AND FLUORESCENT ACTIVITIES AND APPLICATIONS THEREOF | TAGCYX BIOTECHNOLOGIES C/O RIKEN (JP) | 2013-05-16 | — | — | US | claimed |
| EP-1544294-B1 | NUCLEOSIDES OR NUCLEOTIDES HAVING NOVEL UNNATURAL BASES AND USE THEREOF | RIKEN (JP) | 2013-04-10 | — | — | EP | claimed |
| EP-2562255-A1 | NUCLEIC ACID BASE ANALOG WITH QUENCHING CHARACTERISTICS AND FLUORESCENCE AND APPLICATION THEREOF | Riken (JP) | 2013-02-27 | — | — | EP | claimed |
| US-8212014-B2 | Artificial base pairs and uses thereof | RIKEN (JP) | 2012-07-03 | — | — | US | claimed |
| US-20100323364-A1 | MODIFIED tRNA CONTAINING UNNATURAL BASE AND USE THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2010-12-23 | — | — | US | claimed |
| US-20100285598-A1 | Novel Artificial Base Pairs and Uses Thereof | RIKEN (JP) | 2010-11-11 | — | — | US | claimed |
| EP-2246428-A1 | MODIFIED TRNA CONTAINING NON-NATURAL NUCLEOTIDE AND USE THEREOF | The University of Tokyo (JP) | 2010-11-03 | — | — | EP | claimed |
| US-7745417-B2 | Nucleosides or nucleotides having novel unnatural bases and use thereof | RIKEN (JP) | 2010-06-29 | — | — | US | claimed |
| US-7667031-B2 | Nucleic acid base pair | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-02-23 | — | — | US | claimed |
| US-20090275017-A1 | Novel Nucleoside or Nucleotide Derivative and Use Thereof | RIKEN (JP) | 2009-11-05 | — | — | US | claimed |
| EP-1921141-A1 | NOVEL ARTIFICIAL BASE PAIR AND USE THEREOF | Riken (JP) | 2008-05-14 | — | — | EP | claimed |
| EP-1816130-A1 | NOVEL NUCLEOSIDE OR NUCLEOTIDE DERIVATIVE AND USE THEREOF | Riken (JP) | 2007-08-08 | — | — | EP | claimed |
| US-20060263771-A1 | Nucleoside or nucleotides having novel unnatural bases and utilization of the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-11-23 | — | — | US | claimed |
| EP-1544294-A1 | NUCLEOSIDES OR NUCLEOTIDES HAVING NOVEL UNNATURAL BASES AND USE THEREOF | Riken (JP) | 2005-06-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275017-A1 | Novel Nucleoside or Nucleotide Derivative and Use Thereof | DUT, NT5C3B, NT5C | ADORA2A 889/4885DHFR 24/4885ADORA1 1454/4885 |
| US-20100285598-A1 | Novel Artificial Base Pairs and Uses Thereof | POLRMT, RNGTT, POLN | ADORA2A 1513/4885DHFR 396/4885ADORA1 995/4885 |
| US-20100323364-A1 | MODIFIED tRNA CONTAINING UNNATURAL BASE AND USE THEREOF | TRMT1, NSUN3, TARBP1 | ADORA2A 1848/4885DHFR 850/4885ADORA1 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.