Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237900 | 0.91 | SHMT1 (0.41) | ACHESLC6A3DPP4SHMT1SHMT2 | |
| SCHEMBL10237929 | 0.88 | ACHE (0.39) | ACHEPDE4DSLC6A3TP53SHMT1 | |
| SCHEMBL10237926 | 0.86 | GRM2 (0.39) | ACHEPDE4DSLC6A3TP53SHMT1 | |
| SCHEMBL10238058 | 0.86 | ALDH1A1 (0.37) | ACHEPDE4DTP53EGFRKDM4E | |
| SCHEMBL10238141 | 0.85 | ACHE (0.35) | ACHEAGPAT2HTR2BPDE4DSLC6A3 | |
| SCHEMBL10237905 | 0.84 | ACHE (0.37) | ACHESHMT1SHMT2 | |
| SCHEMBL10237934 | 0.83 | RAB9A (0.40) | ACHESLC6A3KDM4EMAPTPOLB | |
| SCHEMBL10237915 | 0.82 | SLC6A3 (0.39) | ACHEPDE4DSLC6A3KDM4EMAPT | |
| SCHEMBL16215997 | 0.82 | SLC6A3 (0.39) | ACHEPDE4DSLC6A3KDM4EMAPT | |
| SCHEMBL10238030 | 0.81 | HTR2C (0.44) | ACHESLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541594-B2 | — | — | 2013-09-24 | — | — | US | disclosed |
| US-8541594-B2 | — | — | 2013-09-24 | — | — | US | disclosed |
| US-20120040826-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20120040826-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040826-A1 | NOVEL HERBICIDES | DDT, HDHD5, DDC | ACHE 120/4885AGPAT2 1093/4885HTR2B 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.