SCHEMBL1031545

SCHEMBL1031545

NC1(c2ccccc2-c2ccc(N(c3ccccc3)c3cccc4ccccc34)cc2)C=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083548 0.91
SCHEMBL22779286 0.78 SIGMAR1 (0.35) SIGMAR1
SCHEMBL17740514 0.76 SIGMAR1 (0.43) SIGMAR1
SCHEMBL19942609 0.76 SIGMAR1 (0.30) SIGMAR1
SCHEMBL17470350 0.75 SIGMAR1 (0.42) SIGMAR1
SCHEMBL28668392 0.75 SLC6A3 (0.41)
SCHEMBL13792975 0.74 SIGMAR1 (0.33) SIGMAR1
SCHEMBL10135976 0.73 CA12 (0.46) SIGMAR1
SCHEMBL17811581 0.73 SIGMAR1 (0.41) SIGMAR1
SCHEMBL12636552 0.73 SIGMAR1 (0.41) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791926-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(10) LG CHEMICAL LTD (KR) 2016-08-31 EP disclosed
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 US disclosed
EP-1926795-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(1) LG CHEMICAL LTD (KR) 2011-01-19 EP disclosed
US-7842404-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-11-30 US disclosed
US-7838129-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-11-23 US disclosed
US-7811682-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-10-12 US disclosed
EP-1794258-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(4) LG CHEMICAL LTD (KR) 2010-09-01 EP disclosed
US-7785720-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-08-31 US disclosed
US-20100065828-A1 COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEM, LTD. (KR) 2010-03-18 US disclosed
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-08-13 US disclosed
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-12-11 US disclosed
US-20080093983-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2008-04-24 US disclosed
US-20070247059-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same CYBA, LOXL1, OGDH SIGMAR1 3870/4885
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same PPOX, CRY1, CRY2 SIGMAR1 4092/4885
US-20100065828-A1 COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME VDAC1, PER2, PPOX SIGMAR1 1904/4885
US-20070247059-A1 Compound and Organic Light Emitting Device Using the Same PPOX, CRY1, CRY2 SIGMAR1 4092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.