SCHEMBL103220

SCHEMBL103220

O=C(CS[Au])Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HSD17B10 Q99714 3/20 0.57
ALDH1A1 P00352 2/20 0.57
EPHX2 P34913 1/20 0.55
MAPT P10636 2/20 0.55
GAA P10253 2/20 0.55
SCN1A P35498 1/20 0.55
SCN2A Q99250 1/20 0.55
SCN3A Q9NY46 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
KDM4E B2RXH2 1/20 0.54
NPC1 O15118 1/20 0.53
POLB P06746 1/20 0.53
NAPRT Q6XQN6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7225647 0.84 TSHR (0.57) TSHRSMN1; SMN2HSD17B10ALDH1A1EPHX2
SCHEMBL9126255 0.83 L3MBTL1 (0.72) TSHRSMN1; SMN2HSD17B10ALDH1A1EPHX2
SCHEMBL13652653 0.81 HSD17B10 (0.67) TSHRSMN1; SMN2HSD17B10ALDH1A1MAPT
SCHEMBL4279652 0.80 SMN1; SMN2 (0.57) TSHRSMN1; SMN2HSD17B10ALDH1A1EPHX2
SCHEMBL19841939 0.79 SMN1; SMN2 (0.58) TSHRSMN1; SMN2HSD17B10ALDH1A1EPHX2
SCHEMBL8634488 0.79 HTT (0.54) TSHRSMN1; SMN2HSD17B10ALDH1A1EPHX2
SCHEMBL13333916 0.79 MAPT (0.57) TSHRSMN1; SMN2HSD17B10ALDH1A1EPHX2
SCHEMBL6796256 0.78 ALDH1A1 (0.78) TSHRSMN1; SMN2HSD17B10ALDH1A1MAPT
SCHEMBL1689206 0.78 EPHX2 (0.68) TSHRSMN1; SMN2EPHX2MAPTGAA
SCHEMBL19255208 0.78 MAPT (0.59) TSHRHSD17B10EPHX2MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117618346-A Ioethalamine suspension, preparation method thereof, ioethalamine suspension, preparation method thereof and application thereof 四川德合制药有限公司 2024-03-01 CN claimed
WO-2021054927-A2 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS SOUTH DAKOTA BOARD OF REGENTS (US) 2021-03-25 WO claimed
US-20200048305-A1 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS SOUTH DAKOTA BOARD OF REGENTS (US) 2020-02-13 US claimed
CN-109647506-A A kind of load type gold catalyst preparation method and purposes 华东理工大学 2019-04-19 CN claimed
US-9622969-B2 Polymer conjugated protein micelles SOUTH DAKOTA STATE UNIV (US) 2017-04-18 US claimed
US-20140370110-A1 POLYMER CONJUGATED PROTEIN MICELLES SOUTH DAKOTA STATE UNIVERSITY (US) 2014-12-18 US claimed
EP-0819739-B1 Hot-melt ink composition BROTHER IND LTD (JP) 2001-10-24 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1089705-A1 STICK-SHAPED COSMETIC COMPOSITIONS Cognis Deutschland GmbH (DE) 2001-04-11 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-1999066895-A1 STICK-SHAPED COSMETIC COMPOSITIONS COGNIS DEUTSCHLAND GMBH (DE) 1999-12-29 WO claimed
EP-0676454-B1 Hot melt ink utilizable for ink jet printer BROTHER IND LTD (JP) 1999-10-27 EP claimed
EP-0181198-B1 HOT MELT IMPULSE INK JET INK DATAPRODUCTS CORPORATION (US) 1992-04-15 EP claimed
EP-3442354-B1 FORMULATION AND PRODUCTION OF SPINACH EXTRACT WITH BETA ECDYSON DR GOETZ GMBH (DE) 2026-05-20 EP disclosed
US-12594257-B2 Means and methods for improving anti-tumoral efficacy of transmembrane channel protein blockers ARDAN PHARMA S.A.S. (AR) 2026-04-07 US disclosed
US-12569414-B2 Sunscreen compositions containing porous metal oxide spheres BASF SE (DE) 2026-03-10 US disclosed
EP-0002243-B1 SOLID COMPOSITIONS BASED ON PHOSPHITES STABILISED AGAINST HYDROLYSIS FOR STABILISING POLYOLEFINS HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-02 EP disclosed
EP-0037375-A1 Insecticidal-vapours emitting device Airwick AG (CH) 1981-10-07 EP disclosed
EP-0036385-A2 Insecticidal vapour-emitting compositions on the basis of pyrethrinoids Airwick AG (CH) 1981-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048305-A1 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS GSTK1, GSTO1, GSTM2 TSHR 3941/4885SMN1; SMN2 4125/4885HSD17B10 492/4885
US-20140370110-A1 POLYMER CONJUGATED PROTEIN MICELLES MTDH, PSMG3, GHITM TSHR 3161/4885SMN1; SMN2 1968/4885HSD17B10 3318/4885
US-12594257-B2 Means and methods for improving anti-tumoral efficacy of transmembrane channel protein blockers TMEM94, TMEM126A, TMEM41B TSHR 2430/4885SMN1; SMN2 3859/4885HSD17B10 4083/4885
US-12569414-B2 Sunscreen compositions containing porous metal oxide spheres RAD50, CTSA, MCM7 TSHR 853/4885SMN1; SMN2 2573/4885HSD17B10 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.