Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665032 | 1.00 | L3MBTL1 (0.56) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL17058993 | 0.98 | RAB9A (0.55) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL487755 | 0.98 | RAB9A (0.55) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23011835 | 0.98 | RAB9A (0.55) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1971057 | 0.94 | NFKB1 (0.56) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10144466 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL17053310 | 0.85 | MAPT (0.54) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL487279 | 0.85 | SMN1; SMN2 (0.50) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL17053288 | 0.83 | LPL (0.45) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10715805 | 0.83 | RARB (0.58) | L3MBTL1TDP1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308975-B2 | Substituted imidazo[1,2-a]pyrazines as luciferase substrates | PROMEGA CORPORATION (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180223330-A1 | COELENTERAZINE ANALOGUES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-08-09 | — | — | US | disclosed |
| US-9580425-B2 | Pyrido[3,4-b] indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| EP-0365641-A1 | PYRIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180223330-A1 | COELENTERAZINE ANALOGUES | GLB1, SI, TCF7L2 | L3MBTL1 52/4885TDP1 3852/4885RAB9A 1793/4885 |
| US-10308975-B2 | Substituted imidazo[1,2-a]pyrazines as luciferase substrates | AADAC, PGLS, GLB1 | L3MBTL1 241/4885TDP1 3491/4885RAB9A 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.