Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347968 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHTTALDH1A1RELA | |
| SCHEMBL9455044 | 0.89 | LMNA (0.37) | SMN1; SMN2LMNAHTTALDH1A1RELA | |
| SCHEMBL9744994 | 0.87 | APP (0.38) | SMN1; SMN2LMNAHTTALDH1A1APP | |
| SCHEMBL9455221 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2LMNAHTTALDH1A1RELA | |
| SCHEMBL9455214 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2LMNAHTTALDH1A1RELA | |
| SCHEMBL10600067 | 0.80 | LMNA (0.41) | SMN1; SMN2LMNAHTTALDH1A1RELA | |
| SCHEMBL7044936 | 0.77 | CYP2A6 (0.47) | SMN1; SMN2LMNAHTTALDH1A1TERT | |
| SCHEMBL11398927 | 0.77 | CYP2A6 (0.47) | SMN1; SMN2LMNAHTTALDH1A1TERT | |
| SCHEMBL4688796 | 0.76 | TERT (0.43) | SMN1; SMN2LMNAHTTALDH1A1APP | |
| SCHEMBL372527 | 0.75 | CHAT (0.61) | SMN1; SMN2HTTALDH1A1TERTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56008365-A | — | — | None | — | — | JP | disclosed |
| US-20190091492-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | L'OREAL (FR) | 2019-03-28 | — | — | US | disclosed |
| US-8609074-B2 | Methods for making up a keratinous substrate | L'OREAL (FR) | 2013-12-17 | — | — | US | disclosed |
| US-20130171083-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | L'OREAL S.A. (FR) | 2013-07-04 | — | — | US | disclosed |
| US-20130167859-A1 | METHODS FOR MAKING UP A KERATINOUS SUBSTRATE | L'OREAL S.A. (FR) | 2013-07-04 | — | — | US | disclosed |
| EP-0261981-B1 | PHOTOSENSITIVE RESIN COMPOSITION | Director-General of the Agency of Industrial Science and Technology (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4891300-A | SCREEN PRINTING PLATES | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE AND INDUSTRY (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0130804-B1 | PHOTOSENSITIVE RESIN COMPOSITION | KOGYO GIJUTSUIN (JP) | 1989-02-08 | — | — | EP | disclosed |
| EP-0261981-A2 | Photosensitive resin composition | Director-General of the Agency of Industrial Science and Technology (JP) | 1988-03-30 | — | — | EP | disclosed |
| US-4564580-A | SAPONIFIED VINYL ACETATE POLYMER REACTED WITH STRYLPYRIDINIUM OR S | KOGYO GIJUTSUIN (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0130804-A2 | Photosensitive resin composition | KOGYO GIJUTSUIN (JP) | 1985-01-09 | — | — | EP | disclosed |
| US-4339524-A | VINYL ACETATE, VINYL ALCOHOL ACETAL | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE AND INDUSTRY (JP) | 1982-07-13 | — | — | US | disclosed |
| US-4287335-A | WHEREIN SAID COMPOUND IS A STYRYLPYRIDINIUM SALT OR A STYRYLQUINOLINIUM SALT USEFUL IN PRODUCING A PHOTOSENSITIVE RESIN | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1981-09-01 | — | — | US | disclosed |
| US-4272620-A | Polyvinyl alcohol-styrylpyridinium photosensitive resins and method for manufacture thereof | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1981-06-09 | — | — | US | disclosed |
| JP-S568365-A | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS BEARING ACETAL GROUPS AND ITS PRODUCTION | AGENCY OF IND SCIENCE & TECHNOL | 1981-01-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171083-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | KRT18, PLOD3, LCP1 | SMN1; SMN2 3734/4885LMNA 706/4885HTT 2733/4885 |
| US-20190091492-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | KRT18, PLOD3, LCP1 | SMN1; SMN2 3734/4885LMNA 706/4885HTT 2733/4885 |
| US-20130167859-A1 | METHODS FOR MAKING UP A KERATINOUS SUBSTRATE | KRT18, DSG1, CUTA | SMN1; SMN2 4309/4885LMNA 378/4885HTT 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.