Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11037762 | 0.96 | DNM1 (0.55) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| SCHEMBL187428 | 0.96 | — | — | |
| SCHEMBL10415439 | 0.96 | DNM1 (0.60) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL156326 | 0.92 | CYP3A4 (0.62) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| Iodide SCHEMBL2911216 | 0.92 | DNM1 (0.57) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| SCHEMBL10415438 | 0.92 | DNM1 (0.57) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| Bromide SCHEMBL2916839 | 0.92 | MEN1 (0.62) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| SCHEMBL10002124 | 0.92 | DNM1 (0.57) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| Fluoride Ion SCHEMBL11797943 | 0.92 | DNM1 (0.57) | DNM1MEN1LMNAKMT2ACYP3A4 | |
| Water SCHEMBL11782804 | 0.90 | DNM1 (0.50) | DNM1MEN1LMNAKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 929 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042976-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM ELECTRONIC MAT USA INC (US) | 2026-02-12 | — | — | US | claimed |
| US-12312569-B2 | Kit for cleaning agent and method for preparing cleaning agent | FUJIFILM CORPORATION (JP) | 2025-05-27 | — | — | US | claimed |
| US-12292689-B2 | Alkaline cleaning composition, cleaning method, and manufacturing method of semiconductor | DAXIN MATERIALS CORPORATION (TW) | 2025-05-06 | — | — | US | claimed |
| CN-114672378-B | Alkaline cleaning composition, cleaning method and semiconductor manufacturing method | 达兴材料股份有限公司 | 2024-08-13 | — | — | CN | claimed |
| US-20240262964-A1 | METHOD OF PRODUCING SILICONE POLYMER | TORAY FINE CHEMICALS CO., LTD. (JP) | 2024-08-08 | — | — | US | claimed |
| CN-118092091-A | Reducing chip photoresist stripping liquid, preparation method and application thereof | 浙江奥首材料科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| EP-4361201-A1 | METHOD FOR PRODUCING SILICONE POLYMER | Toray Fine Chemicals Co., Ltd. (JP) | 2024-05-01 | — | — | EP | claimed |
| CN-117413005-A | Process for producing siloxane polymer | 东丽精细化工株式会社 | 2024-01-16 | — | — | CN | claimed |
| US-20230420266-A1 | COMPOSITION FOR TREATING SEMICONDUCTOR AND METHOD FOR TREATING OBJECT TO BE TREATED | FUJIFILM CORPORATION (JP) | 2023-12-28 | — | — | US | claimed |
| EP-3037889-B1 | MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KK (JP) | 2023-11-29 | — | — | EP | claimed |
| US-20070100153-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED POLYORGANOSILOXANES | GOLDSCHMIDT GMBH (DE) | 2007-05-03 | — | — | US | claimed |
| EP-1135330-A4 | SYNTHESIS OF AND COMPOSITIONS OF ECR-40, LARGE PORE ALUMINOPHOSPHATE | EXXONMOBIL RES & ENG CO (US) | 2005-11-16 | — | — | EP | claimed |
| US-20030171239-A1 | Methods and compositions for chemically treating a substrate using foam technology | EKC TECHNOLOGY, INC. | 2003-09-11 | — | — | US | claimed |
| WO-2003064581-A1 | METHODS AND COMPOSITIONS FOR CHEMICALLY TREATING A SUBSTRATE USING FOAM TECHNOLOGY | EKC TECHNOLOGY, INC. (US) | 2003-08-07 | — | — | WO | claimed |
| US-6379500-B2 | Silica-based sols | AKZO NOBEL NV (NL) | 2002-04-30 | — | — | US | claimed |
| EP-1135330-A1 | SYNTHESIS OF AND COMPOSITIONS OF ECR-40, LARGE PORE ALUMINOPHOSPHATE | ExxonMobil Research and Engineering Company (US) | 2001-09-26 | — | — | EP | claimed |
| US-20010004927-A1 | Aqueous silica-based sol comprising a nitrogen-containing organic compound and silica-based particles with a specific surface area of atleast 300 square meters/gram of silica having S-valule 10-60% | AKZO NOBEL NV (NL) | 2001-06-28 | — | — | US | claimed |
| WO-2000021884-A1 | SYNTHESIS OF AND COMPOSITIONS OF ECR-40, LARGE PORE ALUMINOPHOSPHATE | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 2000-04-20 | — | — | WO | claimed |
| US-5976491-A | Synthesis of and composition of ECR-40, large pore aluminophosphate | EXXON RESEARCH AND ENGINEERING CO. (US) | 1999-11-02 | — | — | US | claimed |
| EP-0267437-A2 | Means and process for the removal of photo-resists | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-05-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100153-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED POLYORGANOSILOXANES | ADH1C, ADH1A, SORD | DNM1 389/4885MEN1 2025/4885LMNA 1946/4885 |
| US-20260042976-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | ACP1, PLOD1, CA1 | DNM1 2769/4885MEN1 2500/4885LMNA 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.