Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165222 | 0.83 | F11 (0.40) | ALDH1A1KDM4EXDH | |
| SCHEMBL10429327 | 0.77 | XDH (0.47) | XDH | |
| SCHEMBL10429323 | 0.76 | MAOB (0.40) | XDH | |
| SCHEMBL10429321 | 0.72 | ADORA3 (0.39) | ALDH1A1SMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL10429340 | 0.72 | NOTUM (0.39) | ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL10429313 | 0.71 | NOTUM (0.38) | ALDH1A1KDM4ESMN1; SMN2KMT2APOLB | |
| SCHEMBL10429339 | 0.71 | NPC1 (0.33) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL10429350 | 0.71 | KDR (0.36) | ALDH1A1 | |
| SCHEMBL10429322 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10429364 | 0.71 | NOTUM (0.33) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274654-A2 | 1,2,3-Triazin-4(3H)-one derivatives, process for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1988-07-20 | — | — | EP | claimed |
| US-4920119-A | XANTHINE OXIDASE INHIBITORS; CONTROL OR PREVENTION OF GOUT OR ISCHEMIA | HOFFMANN-LA ROCHE INC. (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0274654-A2 | 1,2,3-Triazin-4(3H)-one derivatives, process for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1988-07-20 | — | — | EP | disclosed |