Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755253 | 0.82 | CES1 (0.70) | ACHECES1CES2HDAC6PARP1 | |
| SCHEMBL13967266 | 0.81 | ENPP2 (0.44) | ACHEMGLLENPP2KDM4EALDH1A1 | |
| SCHEMBL3784519 | 0.80 | CES1 (0.45) | ACHECES1MGLL | |
| SCHEMBL30166168 | 0.80 | CES1 (0.65) | ACHECES1CES2HDAC6PARP1 | |
| SCHEMBL1273634 | 0.80 | CES1 (0.65) | ACHECES1CES2HDAC6PARP1 | |
| SCHEMBL19321680 | 0.79 | ENPP2 (0.48) | CES1MGLLENPP2CES2KDM4E | |
| SCHEMBL1046198 | 0.76 | CES1 (0.56) | CES1MGLL | |
| SCHEMBL29380260 | 0.76 | TTR (0.59) | MGLLENPP2KDM4EALDH1A1 | |
| SCHEMBL6684 | 0.76 | TTR (0.59) | MGLLENPP2KDM4EALDH1A1 | |
| SCHEMBL5136 | 0.75 | PARP1 (0.59) | MGLLENPP2KDM4EALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982087-B2 | Method for producing compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-29 | — | — | US | disclosed |
| EP-1306131-B1 | Cross-coupling process using a catalyst comprising a cyclic nitrogen ligand | SUMITOMO CHEMICAL CO (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-20160200861-A1 | METHOD FOR PRODUCING COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-14 | — | — | US | disclosed |
| EP-3037398-A1 | METHOD FOR MANUFACTURING CHEMICAL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2016-06-29 | — | — | EP | disclosed |
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-8501993-B2 | Processes for the preparation of amides | SYNGENTA LIMITED (GB) | 2013-08-06 | — | — | US | disclosed |
| US-20120289707-A1 | PROCESS FOR THE PREPARATION OF AMIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-15 | — | — | US | disclosed |
| US-8227619-B2 | Process for the preparation of amides | SYNGENTA LIMITED (GB) | 2012-07-24 | — | — | US | disclosed |
| US-20110263889-A1 | PROCESSES FOR THE PREPARATION OF ESTERS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110178310-A1 | PROCESS FOR THE PREPARATION OF AMIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-07-21 | — | — | US | disclosed |
| EP-1481967-A1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040167364-A1 | Production method of a coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-26 | — | — | US | disclosed |
| EP-1449580-A1 | Production method of a cross-coupling compound from an alkyl halide and an organoboron compound | Sumitomo Chemical Co.,Ltd. (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-20040161404-A1 | Method for producing coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-19 | — | — | US | disclosed |
| US-20040158093-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-12 | — | — | US | disclosed |
| EP-1439157-A2 | Method for producing Suzuki coupling compound catalysed by a nickel compound | Sumitomo Chemical Co.,Ltd. (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-20030162950-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-28 | — | — | US | disclosed |
| EP-1306131-A2 | Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263889-A1 | PROCESSES FOR THE PREPARATION OF ESTERS | ADH5, CYP3A4, CYP4F3 | ACHE 198/4885CES1 74/4885MGLL 406/4885 |
| US-20030162950-A1 | Coupling catalyst and process using the same | NOD1, PYM1, C9 | ACHE 4445/4885CES1 2726/4885MGLL 3395/4885 |
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | ACHE 3484/4885CES1 1051/4885MGLL 3236/4885 |
| US-20040158093-A1 | Process for preparing a biaryl compound | CYP1B1, REL, CYP2F1 | ACHE 3905/4885CES1 1143/4885MGLL 3334/4885 |
| US-20040167364-A1 | Production method of a coupling compound | PYM1, BRIX1, CXCR1 | ACHE 4596/4885CES1 3088/4885MGLL 4154/4885 |
| US-20110178310-A1 | PROCESS FOR THE PREPARATION OF AMIDES | H1-5, CYP3A5, CYP2B6 | ACHE 231/4885CES1 481/4885MGLL 2206/4885 |
| US-20120289707-A1 | PROCESS FOR THE PREPARATION OF AMIDES | CHRM2, CHRM1, CYP1B1 | ACHE 204/4885CES1 537/4885MGLL 2200/4885 |
| US-20040161404-A1 | Method for producing coupling compound | PYM1, MALT1, BET1 | ACHE 4735/4885CES1 2893/4885MGLL 2530/4885 |
| US-20160200861-A1 | METHOD FOR PRODUCING COMPOUND | NUDT1, OSGEP, CNOT9 | ACHE 2463/4885CES1 3673/4885MGLL 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.