SCHEMBL1047571

SCHEMBL1047571

CS(=O)(=O)OCCSSCCOS(C)(=O)=O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.57
TSHR P16473 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
MMP9 P14780 1/20 0.57
ALOX15 P16050 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18356628 0.91 USP2 (0.48) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL14024388 0.91 USP2 (0.48) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL13016489 0.85 USP2 (0.43) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL20679022 0.83 USP2 (0.57) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL17933584 0.83 USP2 (0.41) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL3248547 0.82 TSHR (0.71) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL6582696 0.81
Ethane Dimethane Sulfonate SCHEMBL1336145 0.78 USP2 (0.75) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL1957438 0.74 USP2 (0.46) USP2TSHRKDM4EALDH1A1LMNA
Ethane Dimethane Sulfonate SCHEMBL4149477 0.73 USP2 (0.67) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534435-B2 Lipids and nanoparticle compositions thereof GENERATION BIO CO. (US) 2026-01-27 US disclosed
EP-2952541-B1 RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME BRIDGESTONE CORP (JP) 2026-01-14 EP disclosed
US-20250361208-A1 LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF GENERATION BIO CO (US) 2025-11-27 US disclosed
US-12252470-B2 Lipids and nanoparticle compositions thereof GENERATION BIO CO. (US) 2025-03-18 US disclosed
EP-4452942-A1 NANOMATERIALS COMPRISING DISULFIDES Beam Therapeutics Inc. (US) 2024-10-30 EP disclosed
US-20240335542-A1 NANOMATERIALS COMPRISING DISULFIDES BEAM THERAPEUTICS INC. 2024-10-10 US disclosed
US-20240294474-A1 NOVEL LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF GENERATION BIO CO. 2024-09-05 US disclosed
US-20230320993-A1 METHODS FOR ENCAPSULATING POLYNUCLEOTIDES INTO REDUCED SIZES OF LIPID NANOPARTICLES AND NOVEL FORMULATION THEREOF GENERATION BIO CO. 2023-10-12 US disclosed
US-20230320993-A1 METHODS FOR ENCAPSULATING POLYNUCLEOTIDES INTO REDUCED SIZES OF LIPID NANOPARTICLES AND NOVEL FORMULATION THEREOF GENERATION BIO CO. 2023-10-12 US disclosed
WO-2023121964-A1 NANOMATERIALS COMPRISING DISULFIDES BEAM THERAPEUTICS INC. (US) 2023-06-29 WO disclosed
WO-2007110540-A2 DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING AN ALKOXY/HYDROXY GROUPING, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT L'OREAL (FR) 2007-10-04 WO disclosed
US-20060080791-A1 Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye L'OREAL S.A. (FR) 2006-04-20 US disclosed
EP-1647580-A1 Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye. L'OREAL (FR) 2006-04-19 EP disclosed
US-6825187-B2 CARBAPENEM DERIVATIVES SUBSTITUTED AT THE 2-POSITION WITH A SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP; USE AGAINST ANTIBIOTIC RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA, ENTEROCOCCI AND INFLUENZA VIRUS MEIJI SEIKA KAISHA, LTD. (JP) 2004-11-30 US disclosed
EP-1251133-B1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA (JP) 2004-10-13 EP disclosed
US-6680313-B2 1-HYDROXYETHYL-2(IMIDAZO(5,1B)THIAZOL-2-YL-1-CARBAPEN-2-EM-3-C CARBOXYLIC ACID OR SALT, EXCELLENT ANTIBIOTIC ACTIVITY AGAINST A WIDE SPECTRUM OF BACTERIA MEIJI SEIKA KAISHA, LTD. (JP) 2004-01-20 US disclosed
US-20030027809-A1 Novel carbapenum derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2003-02-06 US disclosed
US-20030022881-A1 Novel carbapenem derivatives of quarternary salt type MEIJI SEIKA KAISHA, LTD. (JP) 2003-01-30 US disclosed
EP-1251134-A1 NOVEL CARBAPENEM DERIVATIVES OF QUATERNARY SALT TYPE MEIJI SEIKA KAISHA LTD. (JP) 2002-10-23 EP disclosed
EP-1251133-A1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 2002-10-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534435-B2 Lipids and nanoparticle compositions thereof AGO2, NSUN3, POLRMT USP2 1577/4885TSHR 2912/4885KDM4E 1788/4885
US-20030027809-A1 Novel carbapenum derivatives DHPS, DPEP1, OXA1L USP2 1717/4885TSHR 4709/4885KDM4E 720/4885
US-20240335542-A1 NANOMATERIALS COMPRISING DISULFIDES GPX4, GPX1, ABCB7 USP2 1221/4885TSHR 3231/4885KDM4E 4498/4885
US-20060080791-A1 Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye KRT18, DSG1, DSC1 USP2 1489/4885TSHR 4553/4885KDM4E 1490/4885
US-20240294474-A1 NOVEL LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF LIPG, NPC1L1, NPC1 USP2 3452/4885TSHR 3721/4885KDM4E 3836/4885
US-20230320993-A1 METHODS FOR ENCAPSULATING POLYNUCLEOTIDES INTO REDUCED SIZES OF LIPID NANOPARTICLES AND NOVEL FORMULATION THEREOF POLN, POLRMT, LIPG USP2 2100/4885TSHR 4566/4885KDM4E 3851/4885
US-12252470-B2 Lipids and nanoparticle compositions thereof LIPG, NPC1L1, NPC1 USP2 3815/4885TSHR 3809/4885KDM4E 3966/4885
US-20250361208-A1 LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF LIPG, NPC1L1, NPC1 USP2 3815/4885TSHR 3809/4885KDM4E 3966/4885
US-20030022881-A1 Novel carbapenem derivatives of quarternary salt type DHPS, HDHD5, RRP15 USP2 1667/4885TSHR 4206/4885KDM4E 531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.