Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106444 | 0.70 | — | — | |
| SCHEMBL1336319 | 0.69 | LMNA (0.45) | LMNAFDPSPGK1PGK2ALDH1A1 | |
| SCHEMBL2087244 | 0.69 | LMNA (0.45) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL578487 | 0.69 | FDPS (0.33) | FDPS | |
| SCHEMBL16944043 | 0.67 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL635332 | 0.65 | — | — | |
| SCHEMBL4071999 | 0.65 | — | — | |
| SCHEMBL8563414 | 0.65 | LMNA (0.41) | LMNAFDPSPGK1PGK2MEN1 | |
| SCHEMBL28490987 | 0.63 | LMNA (0.39) | LMNAFDPSPGK1PGK2ALDH1A1 | |
| SCHEMBL992 | 0.63 | DGAT1 (0.41) | LMNAFDPSPGK1PGK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808581-A | ANXIOLYTIC, ANTIEMETIC, TREATMENT OF PSYCHOLOGICAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1989-02-28 | — | — | US | disclosed |